Stefaan Derveaux
Overview
Explore the profile of Stefaan Derveaux including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
895
Followers
0
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Recent Articles
1.
Lippens S, Audenaert D, Botzki A, Derveaux S, Ghesquiere B, Goeminne G, et al.
EMBO Rep
. 2022 Jun;
23(6):e55094.
PMID: 35652151
Core facilities have a different mission than academic research labs. Accordingly, they require different career paths and structures.
2.
Depuydt C, Goosens V, Janky R, DHondt A, De Bleecker J, Noppe N, et al.
Cells
. 2022 May;
11(9).
PMID: 35563815
Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by two mutations in anoctamin-5 (). Our aim was to identify genes and pathways that underlie LGMD-R12 and explain differences in the molecular...
3.
Bekesi A, Abdellaoui S, Holroyd N, Van Delm W, Pardon E, Pauwels J, et al.
Methods Enzymol
. 2018 Nov;
611:607-675.
PMID: 30471702
The structural and functional characterization of large multidomain signaling proteins containing long disordered linker regions represents special methodological and conceptual challenges. These proteins show extreme structural heterogeneity and have complex...
4.
Mestdagh P, Lefever S, Volders P, Derveaux S, Hellemans J, Vandesompele J
Sci Data
. 2016 Jul;
3:160052.
PMID: 27377824
Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles...
5.
Mestdagh P, Hartmann N, Baeriswyl L, Andreasen D, Bernard N, Chen C, et al.
Nat Methods
. 2014 Jun;
11(8):809-15.
PMID: 24973947
MicroRNAs are important negative regulators of protein-coding gene expression and have been studied intensively over the past years. Several measurement platforms have been developed to determine relative miRNA abundance in...
6.
De Wilde B, Lefever S, Dong W, Dunne J, Husain S, Derveaux S, et al.
BMC Genomics
. 2014 Mar;
15:184.
PMID: 24612714
Background: Next generation targeted resequencing is replacing Sanger sequencing at high pace in routine genetic diagnosis. The need for well validated, high quality enrichment platforms to complement the bench-top next...
7.
Ruijter J, Pfaffl M, Zhao S, Spiess A, Boggy G, Blom J, et al.
Methods
. 2012 Sep;
59(1):32-46.
PMID: 22975077
RNA transcripts such as mRNA or microRNA are frequently used as biomarkers to determine disease state or response to therapy. Reverse transcription (RT) in combination with quantitative PCR (qPCR) has...
8.
Mestdagh P, Derveaux S, Vandesompele J
Methods Mol Biol
. 2011 Dec;
815:121-30.
PMID: 22130988
MicroRNAs (miRNAs) are small noncoding RNA molecules that function as negative regulators of gene expression. They are essential components of virtually every biological process and deregulated miRNA expression has been...
9.
Vermeulen J, De Preter K, Lefever S, Nuytens J, De Vloed F, Derveaux S, et al.
Nucleic Acids Res
. 2011 Feb;
39(9):e63.
PMID: 21317187
Compromised RNA quality is suggested to lead to unreliable results in gene expression studies. Therefore, assessment of RNA integrity and purity is deemed essential prior to including samples in the...
10.
Derveaux S, Vandesompele J, Hellemans J
Methods
. 2009 Dec;
50(4):227-30.
PMID: 19969088
Reverse transcription quantitative PCR (RT-qPCR) is considered today as the gold standard for accurate, sensitive and fast measurement of gene expression. Unfortunately, what many users fail to appreciate is that...