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» Authors » Stacy A Kujawa

Stacy A Kujawa

Explore the profile of Stacy A Kujawa including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 78
Followers 0
Related Specialties
Cell Biology
Endocrinology
Reproductive Medicine
Top 10 Co-Authors
Shimeng Liu
Ping Yin
Serdar E Bulun
Ariel J Dotts
Hong Zhao
John S Coon V
Zhiyong Dong
John S Coon 5th
Jingting Xu
Yang Dai
Published In
Oncogene
Fertil Steril
Reprod Sci
Biomed Res Int
Adipocyte
Affiliations
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Recent Articles
1.
Tryptophan 2,3-Dioxygenase-2 in Uterine Leiomyoma: Dysregulation by MED12 Mutation Status
Hutchinson A, Yin P, Neale I, Coon 5th J, Kujawa S, Liu S, et al.
Reprod Sci . 2022 Jan; 29(3):743-749. PMID: 35064560
Uterine leiomyomas (fibroids) are common benign tumors in women. The tryptophan metabolism through the kynurenine pathway plays important roles in tumorigenesis in general. Leiomyomas expressing mutated mediator complex subunit 12...
2.
Progesterone receptor-DNA methylation crosstalk regulates depletion of uterine leiomyoma stem cells: A potential therapeutic target
Liu S, Yin P, Xu J, Dotts A, Kujawa S, Coon V J, et al.
Stem Cell Reports . 2021 Aug; 16(9):2099-2106. PMID: 34388365
Uterine leiomyoma (LM) is the most common tumor in women. Via its receptor (PGR) expressed in differentiated LM cells, progesterone stimulates paracrine signaling that induces proliferation of PGR-deficient LM stem...
3.
Identification of core gene in obese type 2 diabetes patients using bioinformatics analysis
Dong Z, Lei X, Kujawa S, Bolu N, Zhao H, Wang C
Adipocyte . 2021 Jun; 10(1):310-321. PMID: 34085602
Adipocytes and adipocyte lipid metabolism are closely related with obesity and type 2 diabetes, but the molecular mechanism still needs further investigation. The aim of this study is to discover...
4.
Activation of protein kinase B by WNT4 as a regulator of uterine leiomyoma stem cell function
Liu S, Yin P, Dotts A, Kujawa S, Coon V J, Wei J, et al.
Fertil Steril . 2020 Sep; 114(6):1339-1349. PMID: 32892998
Objective: To investigate the functional interaction between the Wnt/β-catenin and protein kinase B (Akt) pathways in leiomyoma stem cells (LSC). Design: Laboratory study. Setting: Research laboratory. Patient(s): Premenopausal women (n...
5.
Targeting DNA Methylation Depletes Uterine Leiomyoma Stem Cell-enriched Population by Stimulating Their Differentiation
Liu S, Yin P, Xu J, Dotts A, Kujawa S, Coon V J, et al.
Endocrinology . 2020 Aug; 161(10). PMID: 32812024
Uterine leiomyoma (LM) is the most common tumor in women and can cause severe morbidity. Leiomyoma growth requires the maintenance and proliferation of a stem cell population. Dysregulated deoxyribonucleic acid...
6.
Predicting MicroRNA Target Genes and Identifying Hub Genes in IIA Stage Colon Cancer Patients Using Bioinformatics Analysis
Dong Z, Lin W, Kujawa S, Wu S, Wang C
Biomed Res Int . 2019 Mar; 2019:6341967. PMID: 30881993
Background: Colon cancer is a heterogeneous disease, differing in clinical symptoms, epigenetics, and prognosis for each individual patient. Identifying the core genes is important for early diagnoses and it provides...
7.
Progesterone receptor integrates the effects of mutated MED12 and altered DNA methylation to stimulate RANKL expression and stem cell proliferation in uterine leiomyoma
Liu S, Yin P, Kujawa S, Coon 5th J, Okeigwe I, Bulun S
Oncogene . 2018 Dec; 38(15):2722-2735. PMID: 30538295
Progesterone and its receptor, PR, are essential for uterine leiomyoma (LM, a.k.a., fibroid) tumorigenesis, but the underlying cellular and molecular mechanisms remain unclear. The receptor activator of NF-κB (RANKL) was...