Stacie M Anderson
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Explore the profile of Stacie M Anderson including associated specialties, affiliations and a list of published articles.
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29
Citations
1413
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Recent Articles
1.
Xiang G, He X, Giardine B, Isaac K, Taylor D, McCoy R, et al.
Genome Res
. 2024 Jul;
34(7):1089-1105.
PMID: 38951027
Knowledge of locations and activities of -regulatory elements (CREs) is needed to decipher basic mechanisms of gene regulation and to understand the impact of genetic variants on complex traits. Previous...
2.
Xiang G, He X, Giardine B, Isaac K, Taylor D, McCoy R, et al.
bioRxiv
. 2023 Apr;
PMID: 37066352
Knowledge of locations and activities of cis-regulatory elements (CREs) is needed to decipher basic mechanisms of gene regulation and to understand the impact of genetic variants on complex traits. Previous...
3.
Xiang G, Giardine B, An L, Sun C, Keller C, Heuston E, et al.
BMC Bioinformatics
. 2023 Mar;
24(1):102.
PMID: 36941541
Background: Epigenetic modification of chromatin plays a pivotal role in regulating gene expression during cell differentiation. The scale and complexity of epigenetic data pose significant challenges for biologists to identify...
4.
Feng X, Cheng X, Zheng P, Li Y, Hakim J, Zhang S, et al.
Brain
. 2022 Jul;
146(1):278-294.
PMID: 35867854
Spinal bulbar muscular atrophy (SBMA), the first identified CAG-repeat expansion disorder, is an X-linked neuromuscular disorder involving CAG-repeat-expansion mutations in the androgen receptor (AR) gene. We utilized CRISPR-Cas9 gene editing...
5.
Keller C, Wixom A, Heuston E, Giardine B, Hsiung C, Long M, et al.
G3 (Bethesda)
. 2021 Mar;
11(6).
PMID: 33788948
Chromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with...
6.
Heuston E, Keller C, Lichtenberg J, Giardine B, Anderson S, Hardison R, et al.
Epigenetics Chromatin
. 2018 May;
11(1):22.
PMID: 29807547
Background: Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories of active regulatory elements are in regions of open chromatin, and...
7.
OBrien K, Farrar J, Vlachos A, Anderson S, Tsujiura C, Lichtenberg J, et al.
Blood
. 2017 Apr;
129(23):3111-3120.
PMID: 28377399
Diamond-Blackfan anemia (DBA) is a congenital bone marrow failure syndrome characterized by erythroid hypoplasia, usually without perturbation of other hematopoietic lineages. Approximately 65% of DBA patients with autosomal dominant inheritance...
8.
Wu T, Ji Y, Moseman E, Xu H, Manglani M, Kirby M, et al.
Sci Immunol
. 2016 Dec;
1(6).
PMID: 28018990
During chronic viral infections and in cancer, T cells become dysfunctional, a state known as T cell exhaustion. Although it is well recognized that memory CD8 T cells account for...
9.
Vilboux T, Malicdan M, Chang Y, Guo J, Zerfas P, Stephen J, et al.
J Med Genet
. 2016 Apr;
53(5):318-29.
PMID: 27095636
Background: Laminins are heterotrimeric complexes, consisting of α, β and γ subunits that form a major component of basement membranes and extracellular matrix. Laminin complexes have different, but often overlapping,...
10.
Gomez-Rodriguez J, Meylan F, Handon R, Hayes E, Anderson S, Kirby M, et al.
Nat Commun
. 2016 Mar;
7:10857.
PMID: 26936133
Th9 cells produce interleukin (IL)-9, a cytokine implicated in allergic asthma and autoimmunity. Here we show that Itk, a mediator of T cell receptor signalling required for Th2 immune responses...