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Stacey Efstathiou

Explore the profile of Stacey Efstathiou including associated specialties, affiliations and a list of published articles. Areas
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Articles 41
Citations 1369
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Recent Articles
1.
Arbuckle J, Vogel J, Efstathiou S, Kristie T
mBio . 2023 Jan; 14(1):e0354222. PMID: 36692302
Transcription of herpes simplex virus 1 (HSV-1) immediate early (IE) genes is controlled at multiple levels by the cellular transcriptional coactivator, HCF-1. HCF-1 is complexed with epigenetic factors that prevent...
2.
Poccardi N, Rousseau A, Haigh O, Takissian J, Naas T, Deback C, et al.
J Virol . 2019 Sep; 93(24). PMID: 31554680
Ocular herpes simplex keratitis (HSK) is a consequence of viral reactivations from trigeminal ganglia (TG) and occurs almost exclusively in the same eye in humans. In our murine oro-ocular (OO)...
3.
Edgar R, Stangherlin A, Nagy A, Nicoll M, Efstathiou S, ONeill J, et al.
Proc Natl Acad Sci U S A . 2016 Aug; 113(36):10085-90. PMID: 27528682
Viruses are intracellular pathogens that hijack host cell machinery and resources to replicate. Rather than being constant, host physiology is rhythmic, undergoing circadian (∼24 h) oscillations in many virus-relevant pathways,...
4.
Nicoll M, Hann W, Shivkumar M, Harman L, Connor V, Coleman H, et al.
PLoS Pathog . 2016 Apr; 12(4):e1005539. PMID: 27055281
Herpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced. The only highly expressed viral gene product during latent infection...
5.
Mattiuzzo G, Ashall J, Doris K, MacLellan-Gibson K, Nicolson C, Wilkinson D, et al.
PLoS One . 2015 Nov; 10(11):e0142751. PMID: 26562415
The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification technologies (NAT). The calibration and performance assessment of...
6.
Brennan B, Weber F, Kormelink R, Schnettler E, Bouloy M, Failloux A, et al.
J Gen Virol . 2015 Aug; 96(8):1975-1978. PMID: 26315040
No abstract available.
7.
Rutkowski A, Erhard F, LHernault A, Bonfert T, Schilhabel M, Crump C, et al.
Nat Commun . 2015 May; 6:7126. PMID: 25989971
Herpes simplex virus 1 (HSV-1) is an important human pathogen and a paradigm for virus-induced host shut-off. Here we show that global changes in transcription and RNA processing and their...
8.
Frederico B, May J, Efstathiou S, Stevenson P
J Virol . 2014 Feb; 88(8):3965-75. PMID: 24501409
Unlabelled: Lymphocyte colonization by gammaherpesviruses (γHVs) is an important target for cancer prevention. However, how it works is not clear. Epstein-Barr virus drives autonomous B cell proliferation in vitro but...
9.
Griffiths S, Koegl M, Boutell C, Zenner H, Crump C, Pica F, et al.
PLoS Pathog . 2013 Aug; 9(8):e1003514. PMID: 23950709
Herpes simplex virus type 1 (HSV-1) is a neurotropic virus causing vesicular oral or genital skin lesions, meningitis and other diseases particularly harmful in immunocompromised individuals. To comprehensively investigate the...
10.
Shivkumar M, Milho R, May J, Nicoll M, Efstathiou S, Stevenson P
J Virol . 2013 Aug; 87(19):10477-88. PMID: 23903843
Herpes simplex virus 1 (HSV-1) is a ubiquitous and important human pathogen. It is known to persist in trigeminal ganglia (TG), but how it reaches this site has been difficult...