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Srishti Kotiyal

Explore the profile of Srishti Kotiyal including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 136
Followers 0
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Recent Articles
1.
Kotiyal S, Evason K
Cancers (Basel) . 2021 Aug; 13(16). PMID: 34439356
Hepatocellular carcinoma (HCC) is one of the deadliest human cancers. Activating mutations in the telomerase reverse transcriptase ( promoter ( and gene encoding β-catenin are widespread in HCC (~50% and...
2.
Kotiyal S, Fulbright A, OBrien L, Evason K
J Vis Exp . 2020 Feb; (156). PMID: 32065169
In several transgenic zebrafish models of hepatocellular carcinoma (HCC), hepatomegaly can be observed during early larval stages. Quantifying larval liver size in zebrafish HCC models provides a means to rapidly...
3.
Kalasekar S, Kotiyal S, Conley C, Phan C, Young A, Evason K
Biol Open . 2019 Oct; 8(10). PMID: 31575545
Up to 41% of hepatocellular carcinomas (HCCs) result from activating mutations in the gene encoding β-catenin. HCC-associated mutations stabilize the β-catenin protein, leading to nuclear and/or cytoplasmic localization of β-catenin...
4.
Kotiyal S, Bhattacharya S
Crit Rev Eukaryot Gene Expr . 2016 Aug; 26(2):163-71. PMID: 27480779
EMT is the process by which epithelial cells, characterized by well-developed intercellular contacts, transdifferentiate into motile and invasive mesenchymal cells. This process is associated with the loss of transmembrane intercellular...
5.
Kotiyal S, Bhattacharya S
Crit Rev Eukaryot Gene Expr . 2015 Nov; 25(3):269-80. PMID: 26558950
Vasculogenic mimicry (VM), a newly defined pattern of tumor microvascularization differs from angiogenesis and vasculogenesis in its noninvolvement of endothelial cells, by which highly aggressive tumor cells can form vessel-like...
6.
Kotiyal S, Bhattacharya S
Biochem Biophys Res Commun . 2014 Sep; 453(1):112-6. PMID: 25261721
A small heterogeneous population of breast cancer cells acts as seeds to induce new tumor growth. These seeds or breast cancer stem cells (BCSCs) exhibit great phenotypical plasticity which allows...