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Sriram Jayabal

Explore the profile of Sriram Jayabal including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 527
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Recent Articles
1.
Ferro M, Proctor C, Gonzalez A, Jayabal S, Zhao E, Gagnon M, et al.
AIP Adv . 2024 Aug; 14(8):085109. PMID: 39130131
Scalable electronic brain implants with long-term stability and low biological perturbation are crucial technologies for high-quality brain-machine interfaces that can seamlessly access delicate and hard-to-reach regions of the brain. Here,...
2.
Cook A, Jayabal S, Sheng J, Fields E, Leung T, Quilez S, et al.
Sci Adv . 2022 Sep; 8(37):eabh3260. PMID: 36112675
Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disease resulting in motor coordination deficits and cerebellar pathology. Expression of brain-derived neurotrophic factor (BDNF) is reduced in postmortem tissue from SCA6...
3.
Li L, Jayabal S, Ghorbani M, Legault L, McGraw S, Watt A, et al.
Cell Mol Life Sci . 2019 Apr; 76(18):3621-3640. PMID: 30953095
α-Tubulin acetyltransferase 1 (ATAT1) catalyzes acetylation of α-tubulin at lysine 40 in various organisms ranging from Tetrahymena to humans. Despite the importance in mammals suggested by studies of cultured cells,...
4.
Ljungberg L, Lang-Ouellette D, Yang A, Jayabal S, Quilez S, Watt A
Front Cell Neurosci . 2016 Nov; 10:248. PMID: 27853421
Information is carried out of the cerebellar cortical microcircuit via action potentials propagated along Purkinje cell axons. In several human neurodegenerative diseases, focal axonal swellings on Purkinje cells - known...
5.
Jayabal S, Ljungberg L, Watt A
J Physiol . 2016 Aug; 595(3):949-966. PMID: 27531396
Key Points: Spinocerebellar ataxia type 6 (SCA6) is a midlife-onset neurodegenerative disease caused by a CACNA1A mutation; CACNA1A is also implicated in cerebellar development. We have previously shown that when...
6.
Jayabal S, Chang H, Cullen K, Watt A
Sci Rep . 2016 Jul; 6:29489. PMID: 27381005
Spinocerebellar ataxia type 6 (SCA6) is a devastating midlife-onset autosomal dominant motor control disease with no known treatment. Using a hyper-expanded polyglutamine (84Q) knock-in mouse, we found that cerebellar Purkinje...
7.
Jayabal S, Ljungberg L, Erwes T, Cormier A, Quilez S, Jaouhari S, et al.
eNeuro . 2016 Jan; 2(6). PMID: 26730403
Spinocerebellar ataxia type 6 (SCA6) is an autosomal-dominant cerebellar ataxia that has been associated with loss of cerebellar Purkinje cells. Disease onset is typically at midlife, although it can vary...
8.
Narasimhan K, Pillay S, Huang Y, Jayabal S, Udayasuryan B, Veerapandian V, et al.
Nucleic Acids Res . 2015 Jan; 43(3):1513-28. PMID: 25578969
Sox2 and Pax6 are transcription factors that direct cell fate decision during neurogenesis, yet the mechanism behind how they cooperate on enhancer DNA elements and regulate gene expression is unclear....
9.
Narasimhan K, Hilbig A, Udayasuryan B, Jayabal S, Kolatkar P, Jauch R
Acta Crystallogr F Struct Biol Commun . 2014 Oct; 70(Pt 10):1357-61. PMID: 25286939
Pax genes belong to a family of metazoan transcription factors that are known to play a critical role in eye, ear, kidney and neural development. The mammalian Pax family of...
10.
Ferreira T, Blackman A, Oyrer J, Jayabal S, Chung A, Watt A, et al.
Nat Methods . 2014 Sep; 11(10):982-4. PMID: 25264773
No abstract available.