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Srinivasagam Rajasankar

Explore the profile of Srinivasagam Rajasankar including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 202
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Recent Articles
1.
Raziya Banu M, Ibrahim M, Prabhu K, Rajasankar S
Cells Tissues Organs . 2020 Jan; 208(1-2):59-65. PMID: 31982873
Withaferin-A (WA) was evaluated for its neuroprotective efficacy on the dopamine (DA) neurons of the substantia nigra (SN) and striatum (ST) in aged rats. Wistar albino rats were divided into...
2.
Raziya Banu M, Ibrahim M, Prabhu K, Rajasankar S
Pharmacology . 2018 Dec; 103(3-4):114-119. PMID: 30544122
Withaferin A (WA) was evaluated for its neuro-protective efficacy on ageing induced striatal dopamine (DA) and behavioural changes in aged rats. Wistar albino rats were divided into group I -...
3.
Venkatesh Gobi V, Rajasankar S, Swaminathan Johnson W, Prabu K, Ramkumar M
Front Biosci (Elite Ed) . 2018 Nov; 11(1):12-19. PMID: 30468634
Rotenone is a pesticide that has been shown to induce the pathological symptoms of Parkinson's disease (PD) in both cellular and animal models. In this study, we investigated the protective...
4.
Ramkumar M, Rajasankar S, Swaminathan Johnson W, Prabu K, Venkatesh Gobi V
Front Biosci (Elite Ed) . 2018 Nov; 11(1):1-11. PMID: 30468633
Rotenone, an environmental toxin, is used to induce neurodegeneration in both the cellular and animal model of Parkinson's disease. Demethoxycurcumin (DMC), derivative of curcumin has been reported to have antioxidant...
5.
Ramkumar M, Rajasankar S, Gobi V, Janakiraman U, Manivasagam T, Thenmozhi A, et al.
Pharmacogn Mag . 2018 Mar; 14(53):9-16. PMID: 29576695
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder (NDD) associated with the loss of dopaminergic neurons in the substantia nigra and subsequently has an effect on motor function and...
6.
Venkatesh Gobi V, Rajasankar S, Ramkumar M, Dhanalakshmi C, Manivasagam T, Thenmozhi A, et al.
Nutr Neurosci . 2017 Jun; 21(9):657-666. PMID: 28628424
Neuroinflammation and oxidative damage are the two main malfactors that play an important role in the pathogenesis of experimental and clinical Parkinson's disease (PD). The current study was aimed to...
7.
Ramkumar M, Rajasankar S, Venkatesh Gobi V, Dhanalakshmi C, Manivasagam T, Thenmozhi A, et al.
BMC Complement Altern Med . 2017 Apr; 17(1):217. PMID: 28420370
Background: Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson's disease (PD) and identified as vital objective for therapeutic intercession. This study...
8.
Venkatesh Gobi V, Rajasankar S, Ramkumar M, Dhanalakshmi C, Manivasagam T, Thenmozhi A, et al.
Nutr Neurosci . 2016 Sep; 21(2):97-107. PMID: 27646574
The present study was aimed to find out the effect of Agaricus blazei mushroom extract against rotenone-induced cellular model. SH-SY5Y neuroblastoma cells are divided into four experimental groups (control, rotenone...
9.
Anandhan A, Tamilselvam K, Vijayraja D, Ashokkumar N, Rajasankar S, Manivasagam T
Ann Neurosci . 2014 Sep; 17(3):113-9. PMID: 25205886
Background: Parkinson's disease (PD) is the most common neurodegenerative disorder, characterized by loss of dopaminergic neurons in substantia nigra and depletion of dopamine in striatum due to mitochondrial dysfunction, oxidative...
10.
Surendran S, Rajasankar S
Patholog Res Int . 2011 Sep; 2011:426058. PMID: 21912752
Aspartoacylase/aminoacylase II (ASPA/ACY II) is mainly synthesized in oligodendrocytes to contribute in myelin synthesis. Although axonal damage is seen in the brain with human immunodeficiency virus encephalitis (HIVE), ASPA contribution...