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Srilakshmi Seetharaman

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Articles 9
Citations 51
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Recent Articles
1.
LaHue S, Fuentealba M, Diaz S, Seetharaman S, Garcia T, Furman D, et al.
Geroscience . 2024 Jan; 46(3):3287-3295. PMID: 38246968
Frailty is classically associated with advanced age but is also an important predictor of clinical outcomes in comparatively young adults with cirrhosis. We examined the association of biological aging with...
2.
Berry K, Ruck J, Barry F, Shui A, Cortella A, Kent D, et al.
Clin Transplant . 2023 Dec; 38(1):e15229. PMID: 38113284
Liver transplant (LT) recipients have a high burden of cognitive impairment risk factors identified in other populations, yet little work has explored cognition in the United States LT population. We...
3.
Ha N, Fan B, Seetharaman S, Kent D, Yao F, Shui A, et al.
JGH Open . 2023 Nov; 7(10):724-727. PMID: 37908292
Skeletal muscle index (SMI) remains a strong predictor of mortality in cirrhosis patients. However, the extent to which SMI varies by race/ethnicity has not been fully evaluated. Among 317 patients,...
4.
Wang M, Shui A, Barry F, Verna E, Kent D, Yao F, et al.
Am J Transplant . 2023 Apr; 23(7):966-975. PMID: 37061188
Frailty is a critical determinant of outcomes in cirrhosis patients. The increasing use of telemedicine has created an unmet need for virtual frailty assessment. We aimed to develop a telemedicine-enabled...
5.
Ha N, Seetharaman S, Kent D, Yao F, Shui A, Huang C, et al.
Liver Transpl . 2023 Mar; 29(10):1089-1099. PMID: 36932707
Frailty, a clinical phenotype of decreased physiological reserve, is a strong determinant of adverse health outcomes in patients with cirrhosis. The only cirrhosis-specific frailty metric is the Liver Frailty Index...
6.
Berry K, Asken B, Grab J, Chan B, Lario Lago A, Wong R, et al.
Alzheimers Dement (Amst) . 2022 Jul; 14(1):e12321. PMID: 35845260
Introduction: The impact of hepatorenal function on plasma biomarkers of neuropathology is unknown. Herein, we measured several plasma biomarkers in patients with cirrhosis. Methods: Plasma phosphorylated tau (p-tau181), neurofilament light...
7.
Berry K, Kent D, Seetharaman S, Wong R, Mohamad Y, Yao F, et al.
Ann Hepatol . 2022 Apr; 27(5):100718. PMID: 35460882
Introduction: Loneliness, "a subjective feeling of being isolated", is a strong predictor of adverse health. We characterized loneliness in patients with end-stage liver disease (ESLD) awaiting liver transplantation (LT). Methods:...
8.
Xu C, Yao F, Mohamad Y, Wong R, Kent D, Seetharaman S, et al.
Transplant Direct . 2021 Jan; 7(2):e651. PMID: 33437866
Methods: Included were 247 adult patients with cirrhosis listed for liver transplantation without hepatocellular carcinoma from February 2014 to June 2019, who underwent outpatient assessments using the LFI and KPS...
9.
Wong R, Mohamad Y, Srisengfa Y, Kent D, Seetharaman S, Shah R, et al.
Am J Transplant . 2020 Jun; 21(1):241-246. PMID: 32524691
We examined whether a key psychological trait-resilience, defined as one's ability to recover quickly from difficulties-contributes to the frail phenotype in patients with cirrhosis. Included were 300 adult patients with...