Srilakshmi Chaparala
Overview
Explore the profile of Srilakshmi Chaparala including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
202
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0
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Recent Articles
1.
Wood J, Chaparala S, Bantang C, Chattopadhyay A, Wesesky M, Kinchington P, et al.
J Neurovirol
. 2024 Mar;
30(2):131-145.
PMID: 38478163
The neurogenic niches within the central nervous system serve as essential reservoirs for neural precursor cells (NPCs), playing a crucial role in neurogenesis. However, these NPCs are particularly vulnerable to...
2.
Coppin E, Zhang X, Ohayon L, Johny E, Dasari A, Zheng K, et al.
Arterioscler Thromb Vasc Biol
. 2023 Mar;
43(6):889-906.
PMID: 36891902
Background: Peripheral ischemia caused by peripheral artery disease is associated with systemic inflammation, which may aggravate underlying comorbidities such as atherosclerosis and heart failure. However, the mechanisms of increased inflammation...
3.
Catalina Ardila D, Aggarwal V, Singh M, Chattopadhyay A, Chaparala S, Sant S
Cancers (Basel)
. 2021 Apr;
13(6).
PMID: 33804802
Collective cell migration is a key feature of transition of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) among many other cancers, yet the microenvironmental factors and underlying...
4.
Ganapathiraju M, Subramanian S, Chaparala S, Karunakaran K
Hum Genome Var
. 2020 Dec;
7(1):40.
PMID: 33298903
A palindrome in DNA is like a palindrome in language, but when read backwards, it is a complement of the forward sequence; effectively, the two halves of a sequence complement...
5.
Song S, Huang H, Guan X, Fiesler V, Bhuiyan M, Liu R, et al.
Prog Neurobiol
. 2020 Nov;
199:101963.
PMID: 33249091
The role of astrocytes in dysregulation of blood-brain barrier (BBB) function following ischemic stroke is not well understood. Here, we investigate the effects of restoring the repair properties of astrocytes...
6.
Karunakaran K, Chaparala S, Lo C, Ganapathiraju M
Sci Rep
. 2020 Sep;
10(1):15629.
PMID: 32973177
Cilia are dynamic microtubule-based organelles present on the surface of many eukaryotic cell types and can be motile or non-motile primary cilia. Cilia defects underlie a growing list of human...
7.
Wang Z, Pascal L, Chandran U, Chaparala S, Lv S, Ding H, et al.
Cancer Manag Res
. 2020 Jul;
12:4411-4427.
PMID: 32606936
Background: Elongation factor for RNA polymerase II 2 (ELL2) was reported as a putative tumor suppressor in the prostate. ELL2 is frequently down-regulated in prostatic adenocarcinoma specimens, and loss of...
8.
Karunakaran K, Chaparala S, Ganapathiraju M
Sci Rep
. 2019 Sep;
9(1):12682.
PMID: 31481665
We previously presented the protein-protein interaction network of schizophrenia associated genes, and from it, the drug-protein interactome which showed the drugs that target any of the proteins in the interactome....
9.
Muller S, Agnihotri S, Shoger K, Myers M, Smith N, Chaparala S, et al.
JCI Insight
. 2018 Apr;
3(7).
PMID: 29618666
Low-grade gliomas (LGGs) are the most common brain tumor affecting children. We recently reported an early phase clinical trial of a peptide-based vaccine, which elicited consistent antigen-specific T cell responses...
10.
Pascal L, Wang Y, Zhong M, Wang D, Chakka A, Yang Z, et al.
Neoplasia
. 2018 Mar;
20(4):351-363.
PMID: 29518696
The tumor suppressor genes EAF2 and p53 are frequently dysregulated in prostate cancers. Recently, we reported that concurrent p53 nuclear staining and EAF2 downregulation were associated with high Gleason score....