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Sreenatha S Kirakodu

Explore the profile of Sreenatha S Kirakodu including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 96
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Recent Articles
1.
Ebersole J, Kirakodu S, Zhang X, Dawson 3rd D, Miller C
Sci Rep . 2024 Dec; 14(1):30649. PMID: 39730430
Type 2 diabetes mellitus (T2DM) is associated with cellular abnormalities, tissue and organ dysfunctions, and periodontitis. This investigation examined the relationship between the oral microbiome and salivary biomarkers in T2DM...
2.
Ebersole J, Kirakodu S, Zhang X, Dawson 3rd D, Miller C
Mol Oral Microbiol . 2024 Oct; 40(1):37-49. PMID: 39351619
Objective: To examine the characteristics of the salivary microbiome in Type 2 diabetes mellitus (T2DM) patients with or without periodontitis. Background: Periodontitis has been identified as clear sequelae of T2DM....
3.
Ebersole J, Kirakodu S, Nguyen L, Gonzalez O
Oral Dis . 2024 Apr; 30(8):5274-5293. PMID: 38623775
Objective: This study used an experimental periodontitis model to detail the gingival transcriptome related to cell death processes of pyroptosis, necroptosis, ferroptosis, and cuproptosis. Materials And Methods: Healthy Macaca mulatta...
4.
Ebersole J, Kirakodu S, Nguyen L, Gonzalez O
J Periodontol . 2023 Feb; 94(8):1018-1031. PMID: 36853808
Background: The prevalence and severity of periodontitis demonstrates altered population distribution with age, sex, and race and ethnicity. While males exhibit greater frequency of disease, particularly with aging, the underlying...
5.
Gonzalez O, Kirakodu S, Nguyen L, Ebersole J
Clin Exp Immunol . 2022 Dec; 211(3):248-268. PMID: 36571202
Phenotypic and functional heterogeneity of macrophages is clearly a critical component of their effective functions in innate and adaptive immunity. This investigation hypothesized that altered profiles of gene expression in...
6.
Ebersole J, Nagarajan R, Kirakodu S, Gonzalez O
Mol Immunol . 2022 Jun; 148:18-33. PMID: 35665658
Colonization of mucosal tissues throughout the body occurs by a wide array of bacteria in the microbiome that stimulate the cells and tissues, as well as respond to changes in...
7.
Ebersole J, Kirakodu S, Gonzalez O
Immunology . 2020 Dec; 162(4):405-417. PMID: 33314069
Oral mucosal tissues must react with and respond to microbes comprising the oral microbiome ecology. This study examined the interaction of the microbiome with transcriptomic footprints of apoptosis, autophagy and...
8.
Ebersole J, Kirakodu S, Neumann E, Orraca L, Gonzalez Martinez J, Gonzalez O
Front Immunol . 2020 Nov; 11:585414. PMID: 33193408
This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features...
9.
Ebersole J, Kirakodu S, Novak M, Orraca L, Gonzalez Martinez J, Cunningham L, et al.
Front Immunol . 2016 Aug; 7:272. PMID: 27486459
Evidence has shown activation of T and B cells in gingival tissues in experimental models and in humans diagnosed with periodontitis. The results of this adaptive immune response are noted...
10.
Peyyala R, Kirakodu S, Novak K, Ebersole J
Cytokine . 2012 Jan; 58(1):65-72. PMID: 22266273
Oral bacterial biofilms trigger chronic inflammatory responses in the host that can result in the tissue destructive events of periodontitis. However, the characteristics of the capacity of specific host cell...