Spiros Georgakis
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Explore the profile of Spiros Georgakis including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
38
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Recent Articles
1.
Georgakis S, Ioannidou K, Mora B, Orfanakis M, Brenna C, Muller Y, et al.
Front Immunol
. 2025 Mar;
16:1530327.
PMID: 40070830
Introduction: Systemic lupus erythematosus (SLE) is characterized by dysregulated humoral immunity, leading to the generation of autoreactive B cells that can differentiate both within and outside of lymph node (LN)...
2.
Georgakis S, Orfanakis M, Brenna C, Burgermeister S, Del Rio Estrada P, Gonzalez-Navarro M, et al.
Vaccines (Basel)
. 2024 Aug;
12(8).
PMID: 39204036
Follicular helper CD4 T cells (T) are a major cellular pool for the maintenance of the HIV reservoir. Therefore, the delineation of the follicular (F)/germinal center (GC) immune landscape will...
3.
Moysi E, Sharma A, ODell S, Georgakis S, Del Rio Estrada P, Torres-Ruiz F, et al.
bioRxiv
. 2024 Aug;
PMID: 39131331
A subset of people living with HIV (PLWH) can produce broadly neutralizing antibodies (bNAbs) against HIV, but the lymph node (LN) dynamics that promote the generation of these antibodies are...
4.
Dionysopoulou S, Wikstrom P, Walum E, Georgakis S, Thermos K
Pharmaceuticals (Basel)
. 2024 Mar;
17(3).
PMID: 38543179
Glutamate excitotoxicity and oxidative stress represent two major pathological mechanisms implicated in retinal disorders. In Diabetic Retinopathy (DR), oxidative stress is correlated to NADPH oxidase (NOX), a major source of...
5.
Georgakis S, Dragioti E, Gouva M, Papathanakos G, Koulouras V
Cureus
. 2024 Feb;
16(1):e52912.
PMID: 38406151
A lack of consensus resulting in severe conflicts is often observed between the stakeholders regarding their respective roles in end-of-life (EOL) decision-making in the ICU. Since the burden of these...
6.
Dimou K, Batiridou A, Tatsis F, Georgakis S, Konstanti Z, Papathanakos G, et al.
Cureus
. 2024 Feb;
16(1):e51588.
PMID: 38313939
In the intensive care unit (ICU), patients often experience fragmented memories, primarily comprising dreams and illusions. These experiences can impact psychosocial well-being, correlating with post-traumatic stress symptoms and heightened anxiety....
7.
Dionysopoulou S, Wikstrom P, Bucolo C, Romano G, Micale V, Svensson R, et al.
Diabetes
. 2023 Feb;
72(5):638-652.
PMID: 36821829
Article Highlights: NADPH oxidases (NOXs) are implicated in the early pathological events of diabetic retinopathy (DR). The NOX4 inhibitor GLX7013114, topically administered, reduced oxidative damage and apoptosis in the rat...
8.
Georgakis S, Gkirtzimanaki K, Papadaki G, Gakiopoulou H, Drakos E, Eloranta M, et al.
JCI Insight
. 2021 Sep;
6(21).
PMID: 34554930
IL-33, a nuclear alarmin released during cell death, exerts context-specific effects on adaptive and innate immune cells, eliciting potent inflammatory responses. We screened blood, skin, and kidney tissues from patients...