Sowmya Viswanathan
Overview
Explore the profile of Sowmya Viswanathan including associated specialties, affiliations and a list of published articles.
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57
Citations
1571
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Recent Articles
21.
Hamilton A, Cheung W, Gomez-Aristizabal A, Sharma A, Nakamura S, Chaboureau A, et al.
PLoS One
. 2019 Dec;
14(12):e0214107.
PMID: 31794570
Osteoarthritis (OA) is characterized by cartilage degradation and chronic joint inflammation. Mesenchymal stem cells (MSCs) have shown promising results in OA, but their mechanism of action is not fully understood....
22.
Rockel J, Rabani R, Viswanathan S
Semin Cell Dev Biol
. 2019 Nov;
101:87-103.
PMID: 31757583
Most chronic diseases involving inflammation have a fibrotic component that involves remodeling and excess accumulation of extracellular matrix components. Left unchecked, fibrosis leads to organ failure and death. Mesenchymal stromal...
23.
Rai D, Gurusaran M, Urban V, Aran K, Ma L, Li P, et al.
Sci Rep
. 2019 Oct;
9(1):15519.
PMID: 31664095
State-of-the-art ultra-sensitive blood glucose-monitoring biosensors, based on glucose oxidase (GOx) covalently linked to a single layer graphene (SLG), will be a valuable next generation diagnostic tool for personal glycemic level...
24.
Chisholm J, Ruff C, Viswanathan S
Cytotherapy
. 2019 Jun;
21(7):686-698.
PMID: 31196821
We provide an overview of the regulatory framework, pathways and underlying regulatory authority for cell, gene and tissue-engineered therapies in Canada. Canada's regulatory approach uses three sets of regulations, namely,...
25.
Bubela T, Boch R, Viswanathan S
Front Med (Lausanne)
. 2019 Apr;
6:58.
PMID: 30984761
Canadian academic and industry stakeholders are concerned about the inclusion of "virus-like particles or sub-viral particles" in the definition of which impacts clinical cell and gene therapy and commercialization. The...
26.
Chahal J, Gomez-Aristizabal A, Shestopaloff K, Bhatt S, Chaboureau A, Fazio A, et al.
Stem Cells Transl Med
. 2019 Apr;
8(8):746-757.
PMID: 30964245
Patients with late-stage Kellgren-Lawrence knee osteoarthritis received a single intra-articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM-MSCs) in a phase I/IIa trial to assess...
27.
Chan M, Viswanathan S
Cytotherapy
. 2019 Mar;
21(4):393-415.
PMID: 30871899
Cell-based therapies are a rapidly developing area of regenerative medicine as dynamic treatments that execute therapeutic functions multimodally. Monocytes and macrophages, as innate immune cells that control inflammation and tissue...
28.
Gomez-Aristizabal A, Gandhi R, Mahomed N, Marshall K, Viswanathan S
Arthritis Res Ther
. 2019 Jan;
21(1):26.
PMID: 30658702
Background: Chronic, low-grade inflammation of the synovium (synovitis) is a hallmark of osteoarthritis (OA), thus understanding of OA immunobiology, mediated by immune effectors, is of importance. Specifically, monocytes/macrophages (MΦs) are...
29.
Robb K, Fitzgerald J, Barry F, Viswanathan S
Cytotherapy
. 2018 Dec;
21(3):289-306.
PMID: 30528726
Mesenchymal stromal cell (MSC) therapies have been pursued for a broad spectrum of indications but mixed reports on clinical efficacy have given rise to some degree of skepticism regarding the...
30.
Fink C, Gaudet J, Fox M, Bhatt S, Viswanathan S, Smith M, et al.
Sci Rep
. 2018 Jan;
8(1):590.
PMID: 29330541
A Fluorine (F) perfluorocarbon cell labeling agent, when employed with an appropriate cellular MRI protocol, allows for in vivo cell tracking. F cellular MRI can be used to non-invasively assess...