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Soumyasri Das Gupta

Explore the profile of Soumyasri Das Gupta including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 384
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Recent Articles
1.
Karol S, Alexander T, Budhraja A, Pounds S, Canavera K, Wang L, et al.
Lancet Oncol . 2020 Mar; 21(4):551-560. PMID: 32171069
Background: Outcomes for children with relapsed or refractory acute myeloid leukaemia remain poor. The BCL-2 inhibitor, venetoclax, has shown promising activity in combination with hypomethylating agents and low-dose cytarabine in...
2.
Das Gupta S, Patel M, Wahler J, Bak M, Wall B, Lee M, et al.
Cancer Prev Res (Phila) . 2017 Oct; 10(12):694-703. PMID: 28972008
Despite experimental evidence elucidating the antitumor activities of tocopherols, clinical trials with α-tocopherol (α-T) have failed to demonstrate its beneficial effects in cancer prevention. This study compared the chemopreventive efficacy...
3.
Das Gupta S, Sachs Z
Transl Res . 2017 Aug; 189:123-135. PMID: 28802867
Acute myeloid leukemia (AML) is a lethal malignancy because patients who initially respond to chemotherapy eventually relapse with treatment refractory disease. Relapse is caused by leukemia stem cells (LSCs) that...
4.
Bak M, Das Gupta S, Wahler J, Lee H, Li X, Lee M, et al.
Cancer Prev Res (Phila) . 2017 Jan; 10(3):188-197. PMID: 28096236
Estrogens have been implicated as complete carcinogens for breast and other tissues through mechanisms involving increased cell proliferation, oxidative stress, and DNA damage. Because of their potent antioxidant activity and...
5.
Shan N, Wahler J, Lee H, Bak M, Das Gupta S, Maehr H, et al.
J Steroid Biochem Mol Biol . 2016 Dec; 173:122-129. PMID: 27923595
Triple-negative breast cancer is one of the least responsive breast cancer subtypes to available targeted therapies due to the absence of hormonal receptors, aggressive phenotypes, and the high rate of...
6.
Bak M, Das Gupta S, Wahler J, Suh N
Semin Cancer Biol . 2016 Mar; 40-41:170-191. PMID: 27016037
Estrogen receptor (ER)-positive breast cancer, including luminal-A and -B, is the most common type of breast cancer. Extended exposure to estrogen is associated with an increased risk of breast cancer....
7.
Das Gupta S, Suh N
Mol Nutr Food Res . 2016 Jan; 60(6):1354-63. PMID: 26751721
Tocopherols exist in four forms designated as α, β, δ, and γ. Due to their strong antioxidant properties, tocopherols have been suggested to reduce the risk of cancer. Cancer prevention...
8.
Das Gupta S, Sae-Tan S, Wahler J, So J, Bak M, Cheng L, et al.
Cancer Prev Res (Phila) . 2015 Jul; 8(9):807-16. PMID: 26130252
This study evaluated the anticancer activity and mechanism of action of a γ-tocopherol-rich tocopherol mixture, γ-TmT, in two different animal models of estrogen-induced breast cancer. The chemopreventive effect of γ-TmT...
9.
So J, Wahler J, Das Gupta S, Salerno D, Maehr H, Uskokovic M, et al.
J Steroid Biochem Mol Biol . 2014 Dec; 148:111-21. PMID: 25541438
Tumor-initiating cells (also known as cancer stem cells) are the subpopulation of cells shown to be responsible for tumor initiation, maintenance and recurrence. In breast cancer, CD44(+)/CD24(-/low) cells were identified...
10.
Das Gupta S, So J, Wall B, Wahler J, Smolarek A, Sae-Tan S, et al.
Mol Carcinog . 2014 May; 54(9):916-25. PMID: 24782330
Oxidative stress is known to play a key role in estrogen-induced breast cancer. This study assessed the chemopreventive activity of the naturally occurring γ-tocopherol-rich mixture of tocopherols (γ-TmT) in early...