Sophors Phorl
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Explore the profile of Sophors Phorl including associated specialties, affiliations and a list of published articles.
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5
Citations
46
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Recent Articles
1.
Phorl S, Memon A, Seo Y, Hoang T, Tran T, Nguyen L, et al.
Cancer Sci
. 2022 May;
113(7):2311-2322.
PMID: 35534985
Histone deacetylase 6 (HDAC6), a deacetylase of p53, has emerged as a privileged inhibitory target for cancer therapy because of its deacetylating activity for p53 at K120 and K373/382. However,...
2.
Noh S, Phorl S, Naskar R, Oeum K, Seo Y, Kim E, et al.
Sci Rep
. 2020 Jul;
10(1):10618.
PMID: 32606429
Mitochondria are dynamic organelles that undergo fusion and fission in response to various physiological and stress stimuli, which play key roles in diverse mitochondrial functions such as energy metabolism, intracellular...
3.
Jung S, Han M, Korm S, Lee S, Noh S, Phorl S, et al.
Biochem Biophys Res Commun
. 2018 Jun;
503(1):285-290.
PMID: 29890133
Mitochondrial uncoupling protein 1 (UCP1) is responsible for nonshivering thermogenesis in brown adipose tissue (BAT). UCP1 increases the conductance of the inner mitochondrial membrane (IMM) for protons to make BAT...
4.
Park S, Phorl S, Jung S, Sovannarith K, Lee S, Noh S, et al.
Biochem Biophys Res Commun
. 2017 Oct;
494(1-2):51-56.
PMID: 29054408
The acetylation of p53 is critical in modulating its pro-apoptotic roles. However, its regulatory mechanism and physiological significance are unclear. Here, we show HDAC6 negatively regulates pro-apoptotic acetylation of p53 ...
5.
Chung H, Korm S, Lee S, Phorl S, Noh S, Han M, et al.
Biochem Biophys Res Commun
. 2017 Aug;
492(3):441-446.
PMID: 28842250
RAP80, a member of the BRCA1-A complex, is a well-known crucial regulator of cell cycle checkpoint and DNA damage repair in the nucleus. However, it is still unclear whether Rap80...