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Sophie Taque

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Articles 43
Citations 769
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Recent Articles
1.
Roehrig A, Hirsch T, Pire A, Morcrette G, Gupta B, Marcaillou C, et al.
Nat Commun . 2024 Apr; 15(1):3031. PMID: 38589411
Hepatoblastomas (HB) display heterogeneous cellular phenotypes that influence the clinical outcome, but the underlying mechanisms are poorly understood. Here, we use a single-cell multiomic strategy to unravel the molecular determinants...
2.
Pire A, Hirsch T, Morcrette G, Imbeaud S, Gupta B, Pilet J, et al.
Eur J Cancer . 2024 Feb; 200:113583. PMID: 38330765
Background: Hepatoblastoma is the most frequent pediatric liver cancer. The current treatments lead to 80% of survival rate at 5 years. In this study, we evaluated the clinical relevance of...
3.
Salmon M, Rousseau C, Roussey G, Jay N, Cloarec S, Injeyan M, et al.
Nephrol Ther . 2024 Jan; 20(1):41-49. PMID: 38294263
Introduction: Rheumatoid purpura is the most common vasculitis in children, and its renal involvement determines the prognosis. To date, no national protocol exists for its management. A protocol was drafted...
4.
Pilet J, Hirsch T, Gupta B, Roehrig A, Morcrette G, Pire A, et al.
Nat Commun . 2023 Nov; 14(1):7122. PMID: 37932266
Pediatric liver tumors are very rare tumors with the most common diagnosis being hepatoblastoma. While hepatoblastomas are predominantly sporadic, around 15% of cases develop as part of predisposition syndromes such...
5.
Howley E, Golwala Z, Buckland M, Barzaghi F, Ghosh S, Hackett S, et al.
J Allergy Clin Immunol . 2023 Sep; 153(1):330-334. PMID: 37678573
Background: Newborn screening (NBS) programs for severe combined immunodeficiency facilitate early diagnosis of severe combined immunodeficiency and promote early treatment with hematopoietic stem cell transplantation, resulting in improved clinical outcomes....
6.
Garnier A, Brochard K, Kwon T, Sellier-Leclerc A, Lahoche A, Launay E, et al.
J Am Soc Nephrol . 2023 Jun; 34(9):1561-1573. PMID: 37303085
Significance Statement: Shiga toxin-related hemolytic uremic syndrome (STEC-HUS) is a serious condition, characterized by multiorgan thrombotic microangiopathy, mainly affecting children. Renal involvement is severe, with approximately half of patients requiring...
7.
Semeraro M, Fouquet C, Vial Y, Amiel J, Galmiche L, Cretolle C, et al.
J Pediatr . 2023 May; 259:113451. PMID: 37169337
Objective: To assess the associations between congenital abnormalities and pediatric malignancies and evaluate the potential underlying molecular basis by collecting information on pediatric patients with cancer and congenital abnormalities. Study...
8.
Awounou D, Lacour B, Desandes E, Guissou S, Cassoux N, Doz F, et al.
Cancer Med . 2023 Feb; 12(7):8789-8803. PMID: 36726302
Few studies have investigated the seasonal patterns of embryonal tumours. Based on data from the French National Registry of Childhood Cancers, the present study aimed to investigate seasonal variations in...
9.
Sobrino S, Magnani A, Semeraro M, Martignetti L, Cortal A, Denis A, et al.
Cell Rep Med . 2023 Jan; 4(2):100919. PMID: 36706754
X-linked chronic granulomatous disease (CGD) is associated with defective phagocytosis, life-threatening infections, and inflammatory complications. We performed a clinical trial of lentivirus-based gene therapy in four patients (NCT02757911). Two patients...
10.
Corvest V, Marec-Berard P, Lervat C, Pacquement H, Toulmonde M, Gentet J, et al.
Int J Cancer . 2022 Oct; 152(8):1659-1667. PMID: 36250317
In Euro-EWING99-R1 randomized trial, cyclophosphamide was shown to be noninferior to ifosfamide in the consolidation of standard-risk Ewing sarcoma (SR-EWS) after a common induction with VIDE (vincristine-ifosfamide-doxorubicin-etoposide). We present the...