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Sophie Perinel

Explore the profile of Sophie Perinel including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 292
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Recent Articles
1.
Moreau-Neidhardt M, Leclerc L, Grange J, Perinel S, Pourchez J
Int J Pharm . 2023 Jan; 633:122652. PMID: 36709833
Purpose: This study aims to evaluate the performance of low-cost homemade spacers compared with manufactured valved holding chambers (VHCs) for fluticasone propionate delivery via a pMDI (pressurized Metered Dose Inhaler)....
2.
Cour M, Klouche K, Souweine B, Quenot J, Schwebel C, Perinel S, et al.
Intensive Care Med . 2022 Sep; 48(11):1563-1572. PMID: 36100725
Purpose: To determine whether remote ischemic conditioning (RECO), compared to standard care, limits the severity and the consequences of multiple organ failure in patients with septic shock. Methods: The RECO-Sepsis...
3.
Montigaud Y, Pourchez J, Leclerc L, Tillement O, Clotagatide A, Bal C, et al.
Int J Nanomedicine . 2020 Oct; 15:7251-7262. PMID: 33061379
Purpose: This study aims at determining lung distribution of gadolinium-based polysiloxane nanoparticles, AGuIX (small rigid platform - SRP), as a potential theranostic approach by the pulmonary route. Methods: First, the...
4.
Perinel S, Launay M, Botelho-Nevers E, Diconne E, Louf-Durier A, Lachand R, et al.
Clin Infect Dis . 2020 Apr; 71(16):2227-2229. PMID: 32255489
Hydroxychloroquine (HCQ) appears to be a promising treatment for COVID-19. However, all ongoing clinical trials with HCQ use different dosing regimens, resulting in various concentrations. Pharmacokinetic studies are therefore needed...
5.
Cremillieux Y, Montigaud Y, Bal C, Pinaud N, Pham V, Perinel S, et al.
Magn Reson Med . 2019 Oct; 83(5):1774-1782. PMID: 31654446
Purpose: The objective of this study is to evaluate the suitability and performance of ultra-short echo time (UTE) sequences for imaging and quantifying the deposition of nebulized MRI contrast agents...
6.
Montigaud Y, Perinel S, Dubus J, Leclerc L, Suau M, Goy C, et al.
Sci Rep . 2019 Apr; 9(1):5720. PMID: 30952897
Ethical restrictions are limitations of in vivo inhalation studies, on humans and animal models. Thus, in vitro or ex vivo anatomical models offer an interesting alternative if limitations are clearly...
7.
Perinel S, Forest V, Landraud M, Pourchez J, Girardot F, Riffard S, et al.
Int J Hyg Environ Health . 2017 Nov; 221(2):252-259. PMID: 29174976
Legionella are bacteria responsible for severe lung pathologies. However how they enter and are deposited within the respiratory tract remains poorly documented. Data using animal testing led to the establishment...
8.
Bellomo R, Ronco C, Mehta R, Asfar P, Boisrame-Helms J, Darmon M, et al.
Ann Intensive Care . 2017 May; 7(1):49. PMID: 28474317
The French Intensive Care Society organized its yearly Paris International Conference in intensive care on June 18-19, 2015. The main purpose of this meeting is to gather the best experts...
9.
Perinel S, Pourchez J, Leclerc L, Avet J, Durand M, Prevot N, et al.
Sci Rep . 2017 Feb; 7:43121. PMID: 28233793
Anatomical models to study aerosol delivery impose huge limitations and extrapolation to humans remains controversial. This study aimed to develop and validate an ex vivo human-like respiratory tract model easy...
10.
Aublanc M, Perinel S, Guerin C
Curr Opin Crit Care . 2016 Dec; 23(1):24-29. PMID: 27906708
Purpose Of Review: Acute respiratory distress syndrome (ARDS) mimics is a condition looking like ARDS but that does not fulfill every criterion according to the recent Berlin definition. The purpose...