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Sophie Missbach

Explore the profile of Sophie Missbach including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 41
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Recent Articles
1.
Jebran A, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, et al.
Nature . 2025 Jan; 639(8054):503-511. PMID: 39880949
Cardiomyocytes can be implanted to remuscularize the failing heart. Challenges include sufficient cardiomyocyte retention for a sustainable therapeutic impact without intolerable side effects, such as arrhythmia and tumour growth. We...
2.
Drummer C, Munzker J, Heistermann M, Becker T, Missbach S, Behr R
Animals (Basel) . 2022 Sep; 12(18). PMID: 36139275
Non-human primates (NHPs) serve as embryo donors for embryo collection in order to mimic genetic diseases in humans by genetic modification. Reproductive health of the embryo donors is crucial, and...
3.
Rodriguez-Polo I, Missbach S, Petkov S, Mattern F, Maierhofer A, Grzadzielewska I, et al.
Sci Rep . 2021 Jul; 11(1):15439. PMID: 34326359
Non-human primates (NHPs) are, due to their close phylogenetic relationship to humans, excellent animal models to study clinically relevant mutations. However, the toolbox for the genetic modification of NHPs is...
4.
Moussavi A, Missbach S, Ferrel C, Ghasemipour H, Kotz K, Drummer C, et al.
Sci Rep . 2021 May; 11(1):10713. PMID: 34021218
Cardiac MRI in rhesus macaques, a species of major relevance for preclinical studies on biological therapies, requires artificial ventilation to realize breath holding. To overcome this limitation of standard cine...
5.
Missbach S, Aleksic D, Blaschke L, Hassemer T, Lee K, Mansfeld M, et al.
BMC Evol Biol . 2018 Mar; 18(1):32. PMID: 29544443
Background: The CEA gene family is one of the most rapidly evolving gene families in the human genome. The founder gene of the family is thought to be an ancestor...
6.
Kammerer R, Mansfeld M, Hanske J, Missbach S, He X, Kollner B, et al.
BMC Genomics . 2017 Sep; 18(1):717. PMID: 28893191
Background: Expansions of gene families are predictive for ongoing genetic adaptation to environmental cues. We describe such an expansion of the carcinoembryonic antigen (CEA) gene family in certain bat families....
7.
Aleksic D, Blaschke L, Missbach S, Hanske J, Weiss W, Handler J, et al.
Reproduction . 2016 Jun; 152(3):171-84. PMID: 27280409
Pregnancy-specific glycoproteins (PSGs) are members of the carcinoembryonic antigen cell adhesion molecule (CEACAM) family that are secreted by trophoblast cells. PSGs may modulate immune, angiogenic and platelet responses during pregnancy....