Sophie Darwiche
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Explore the profile of Sophie Darwiche including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
130
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0
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Recent Articles
1.
Ergen F, Naous R, Darwiche S, Hughes J, Da Gama Labo L, Britton C
Skeletal Radiol
. 2024 Dec;
PMID: 39623127
The Achilles tendon is the strongest and largest tendon in the human body, composed of the distal confluence of the gastrocnemius and soleus muscles and may also include the plantaris...
2.
Borhani A, Zhang P, Diergaarde B, Darwiche S, Chuperlovska K, Wang S, et al.
Abdom Radiol (NY)
. 2024 Nov;
PMID: 39487920
Background: Imaging biomarkers are emerging as non-invasive predictors of cancer prognosis and clinical outcome. We assessed tumor-specific ("radiomics") and body composition imaging features ("morphomics") extracted from baseline pre-treatment CT for...
3.
Cong T, Charles S, Greiner J, Cordle A, Andrews C, Darwiche S, et al.
Arthroscopy
. 2024 Feb;
40(9):2363-2369.
PMID: 38403199
Purpose: To determine the comparative accuracy and precision of routine magnetic resonance imaging (MRI) versus magnetic resonance (MR) arthrogram in measuring labral tear size as a function of time from...
4.
Zettel K, Korff S, Zamora R, Morelli A, Darwiche S, Loughran P, et al.
Front Immunol
. 2017 Dec;
8:1672.
PMID: 29234326
Trauma combined with hemorrhagic shock (HS/T) leads to systemic inflammation, which results in organ injury. Toll-like Receptor 4 (TLR4)-signaling activation contributes to the initiation of inflammatory pathways following HS/T but...
5.
Luciano J, Kautza B, Darwiche S, Martinez S, Stratimirovic S, Waltz P, et al.
Shock
. 2015 May;
44 Suppl 1:149-55.
PMID: 26009827
Survival from traumatic injury requires a coordinated and controlled inflammatory and immune response. Mitochondrial and metabolic responses to stress have been shown to play a role in these inflammatory and...
6.
Escobar D, Botero-Quintero A, Kautza B, Luciano J, Loughran P, Darwiche S, et al.
J Surg Res
. 2014 Dec;
194(1):262-72.
PMID: 25456115
Background: Mortality in sepsis is most often attributed to the development of multiple organ failure. In sepsis, inflammation-mediated endothelial activation, defined as a proinflammatory and procoagulant state of the endothelial...
7.
Pfeifer R, Darwiche S, Kohut L, Billiar T, Pape H
Clin Orthop Relat Res
. 2013 Mar;
471(9):2815-21.
PMID: 23479238
Background: In multiply injured patients, bilateral femur fractures invoke a substantial systemic inflammatory impact and remote organ dysfunction. However, it is unclear whether isolated bone or soft tissue injury contributes...
8.
Cai C, Cao Z, Loughran P, Kim S, Darwiche S, Korff S, et al.
J Am Coll Surg
. 2011 Sep;
213(5):604-15.
PMID: 21920785
Background: Much of the morbidity after trauma results from excessive activation of the innate immune system. This is manifested as a systemic inflammatory response and associated end-organ damage. Although mast...
9.
Cai C, Gill R, Eum H, Cao Z, Loughran P, Darwiche S, et al.
Am J Physiol Regul Integr Comp Physiol
. 2010 Aug;
299(5):R1175-82.
PMID: 20702808
Although complement activation is known to occur in the setting of severe hemorrhagic shock and tissue trauma (HS/T), the extent to which complement drives the initial inflammatory response and end-organ...
10.
Schreiber V, Tarkin I, Hildebrand F, Darwiche S, Pfeifer R, Chelly J, et al.
Injury
. 2010 Aug;
42(7):650-4.
PMID: 20701910
Purpose: Early definitive stabilisation is usually the treatment of choice for major fractures in polytrauma patients. Modifications may be made when patients are in critical condition, or when associated injuries...