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Sophia Tsoka

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Articles 67
Citations 1983
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Recent Articles
11.
Avelar P, Del Coco N, Lamb L, Tsoka S, Cardoso-Silva J
Healthc Anal (N Y) . 2023 Jul; 2:100115. PMID: 37520620
Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At...
12.
Crescioli S, Correa I, Ng J, Willsmore Z, Laddach R, Chenoweth A, et al.
Nat Commun . 2023 Jun; 14(1):3378. PMID: 37291228
B cells are known to contribute to the anti-tumor immune response, especially in immunogenic tumors such as melanoma, yet humoral immunity has not been characterized in these cancers to detail....
13.
Chauhan J, Grandits M, Palhares L, Mele S, Nakamura M, Lopez-Abente J, et al.
Nat Commun . 2023 May; 14(1):2192. PMID: 37185332
Outcomes for half of patients with melanoma remain poor despite standard-of-care checkpoint inhibitor therapies. The prevalence of the melanoma-associated antigen chondroitin sulfate proteoglycan 4 (CSPG4) expression is ~70%, therefore effective...
14.
Chen Y, Liu S, Papageorgiou L, Theofilatos K, Tsoka S
Cancers (Basel) . 2023 Mar; 15(6). PMID: 36980673
Background: With advances in high-throughput technologies, there has been an enormous increase in data related to profiling the activity of molecules in disease. While such data provide more comprehensive information...
15.
Brauneck F, Fischer B, Witt M, Muschhammer J, Oelrich J, Avelar P, et al.
J Immunother Cancer . 2022 Dec; 10(12). PMID: 36549780
Background: Leukemia-associated macrophages (LAMs) represent an important cell population within the tumor microenvironment, but little is known about the phenotype, function, and plasticity of these cells. The present study provides...
16.
Bax H, Chauhan J, Stavraka C, Santaolalla A, Osborn G, Khiabany A, et al.
Br J Cancer . 2022 Nov; 128(2):342-353. PMID: 36402875
Background: Survival rates for ovarian cancer remain poor, and monitoring and prediction of therapeutic response may benefit from additional markers. Ovarian cancers frequently overexpress Folate Receptor alpha (FRα) and the...
17.
Adams R, Osborn G, Mukhia B, Laddach R, Willsmore Z, Chenoweth A, et al.
Oncoimmunology . 2022 Oct; 11(1):2127284. PMID: 36211808
The application of monoclonal antibodies (mAbs) for the treatment of melanoma has significantly improved the clinical management of this malignancy over the last decade. Currently approved mAbs for melanoma enhance...
18.
Zain N, Ter Linden D, Lilley A, Royall P, Tsoka S, Bruce K, et al.
J Control Release . 2022 Aug; 350:324-331. PMID: 35963468
Faecal microbiota transplant (FMT) is an established and effective treatment for recurrent Clostridioides difficile infection (CDI) and has many other potential clinical applications. However, preparation and quality of FMT is...
19.
Harris R, Willsmore Z, Laddach R, Crescioli S, Chauhan J, Cheung A, et al.
Oncoimmunology . 2022 Aug; 11(1):2104426. PMID: 35909944
B cells are emerging as key players of anti-tumor adaptive immune responses. We investigated regulatory and pro-inflammatory cytokine-expressing B cells in patients with melanoma by flow cytometric intracellular cytokine, CyTOF,...
20.
OShea R, Rookyard C, Withey S, Cook G, Tsoka S, Goh V
Insights Imaging . 2022 Jun; 13(1):104. PMID: 35715706
Objectives: Radiomic models present an avenue to improve oesophageal adenocarcinoma assessment through quantitative medical image analysis. However, model selection is complicated by the abundance of available predictors and the uncertainty...