Sophia Jeng
Overview
Explore the profile of Sophia Jeng including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
35
Citations
843
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schafer A, Gralinski L, Leist S, Hampton B, Mooney M, Jensen K, et al.
Virus Res
. 2024 Mar;
344:199357.
PMID: 38508400
Coronavirus (CoV) cause considerable morbidity and mortality in humans and other mammals, as evidenced by the emergence of Severe Acute Respiratory CoV (SARS-CoV) in 2003, Middle East Respiratory CoV (MERS-CoV)...
2.
Lin H, Mohammadhosseini M, McClatchy J, Villamor-Paya M, Jeng S, Bottomly D, et al.
Blood
. 2024 Mar;
143(26):2749-2762.
PMID: 38498025
Identifying and targeting microenvironment-driven pathways that are active across acute myeloid leukemia (AML) genetic subtypes should allow the development of more broadly effective therapies. The proinflammatory cytokine interleukin-1β (IL-1β) is...
3.
Medica S, Crawford L, Denton M, Min C, Jones T, Alexander T, et al.
PLoS Pathog
. 2023 Oct;
19(10):e1011682.
PMID: 37782657
Human cytomegalovirus (HCMV) encodes multiple putative G protein-coupled receptors (GPCRs). US28 functions as a viral chemokine receptor and is expressed during both latent and lytic phases of virus infection. US28...
4.
Sinnamon J, Jacobson M, Yung J, Fisk J, Jeng S, McWeeney S, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(33):e2206053119.
PMID: 35939700
Rett syndrome is a neurological disease due to loss-of-function mutations in the transcription factor, Methyl CpG binding protein 2 (MECP2). Because overexpression of endogenous MECP2 also causes disease, we have...
5.
Braun T, Okhovat M, Coblentz C, Carratt S, Foley A, Schonrock Z, et al.
Nat Commun
. 2022 Jun;
13(1):3471.
PMID: 35710794
No abstract available.
6.
Vigoda M, Mathieson C, Evans N, Hale C, Jennings J, Lucero O, et al.
Cancer Biol Ther
. 2022 Mar;
23(1):310-318.
PMID: 35343367
In this study, we report a differential response of mitogen-activated protein kinase-kinase (MEK) inhibitor trametinib in 20 head and neck squamous cell carcinoma (HNSCC) patients' tumor-derived cell cultures. Relatively sensitive...
7.
Romine K, Nechiporuk T, Bottomly D, Jeng S, McWeeney S, Kaempf A, et al.
Blood Cancer Discov
. 2021 Sep;
2(5):518-531.
PMID: 34568834
To understand mechanisms of response to BET inhibitors (BETi), we mined the Beat AML functional genomic dataset and performed genome-wide CRISPR screens on BETi- sensitive and BETi- resistant AML cells....
8.
Schafer A, Gralinski L, Leist S, Winkler E, Hampton B, Mooney M, et al.
bioRxiv
. 2021 May;
PMID: 34013261
Sarbecovirus (CoV) infections, including Severe Acute Respiratory CoV (SARS-CoV) and SARS-CoV-2, are considerable human threats. Human GWAS studies have recently identified loci associated with variation in SARS-CoV-2 susceptibility. However, genetically...
9.
Pallos J, Jeng S, McWeeney S, Martin I
Neurobiol Dis
. 2021 May;
155:105390.
PMID: 33984508
Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common genetic cause of late-onset Parkinson's disease. The pathogenic G2019S mutation enhances LRRK2 kinase activity and induces neurodegeneration in C. elegans,...
10.
Graham J, Swarts J, Edwards K, Voss K, Green R, Jeng S, et al.
Immunohorizons
. 2021 Apr;
5(4):157-169.
PMID: 33893179
The goal of a successful immune response is to clear the pathogen while sparing host tissues from damage associated with pathogen replication and active immunity. Regulatory T cells (Treg) have...