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Soo Jung Shin

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Articles 31
Citations 256
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Recent Articles
11.
Lee S, Park S, Jang G, Lee J, Moon M, Ji Y, et al.
Int J Mol Sci . 2023 Mar; 24(6). PMID: 36982837
Nakai (AK) leaf reportedly ameliorates health problems, such as diabetes. However, the effects of AK on cognitive dysfunction or memory impairment remain unclear. This study investigated whether AK leaf extract...
12.
Kim S, Nam Y, Kim M, Kwon S, Jeon J, Shin S, et al.
J Ginseng Res . 2023 Mar; 47(2):302-310. PMID: 36926613
Background: The most common type of dementia, Alzheimer's disease (AD), is marked by the formation of extracellular amyloid beta (Aβ) plaques. The impairments of axons and synapses appear in the...
13.
Kim S, Nam Y, Shin S, Prajapati R, Shin S, Kim M, et al.
Biomed Pharmacother . 2022 Oct; 156:113865. PMID: 36242849
A prominent characteristic of Alzheimer's disease (AD) is the deposition of both amyloid-β (Aβ) peptide and tau protein in the brain. Aβ and tau not only induce toxicity through self-aggregation...
14.
Kim H, Kim S, Shin S, Park Y, Nam Y, Kim C, et al.
Transl Neurodegener . 2021 Dec; 10(1):49. PMID: 34876226
Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and causes destructive and irreversible cognitive decline. Failures in the development of therapeutics targeting amyloid-β (Aβ) and tau, principal proteins...
15.
Nam Y, Shin S, Park Y, Kim M, Jeon S, Lee H, et al.
Antioxidants (Basel) . 2021 Feb; 10(2). PMID: 33535469
Alzheimer's disease (AD) is a devastating neurodegenerative disease characterized by irreversible cognitive dysfunction. Amyloid beta (Aβ) peptide is an important pathological factor that triggers the progression of AD through accumulation...
16.
Shin S, Nam Y, Park Y, Kim M, Lee E, Jeon S, et al.
Free Radic Biol Med . 2021 Jan; 164:233-248. PMID: 33422674
Biological aging provokes morbidity and several functional declines, causing older adults more susceptible to a variety of diseases than younger adults. In particular, aging is a major risk factor contributing...
17.
Kim S, Nam Y, Shin S, Park Y, Jeon S, Kim J, et al.
Front Neurosci . 2020 Oct; 14:583097. PMID: 33071750
Although the major causative factors of Alzheimer's disease (AD) are the accumulation of amyloid β and hyperphosphorylated tau, AD can also be caused by metabolic dysfunction. The major clinical symptom...
18.
Shin S, Park Y, Jeon S, Kim S, Nam Y, Oh S, et al.
Oxid Med Cell Longev . 2020 Jul; 2020:7829842. PMID: 32685100
Tau, a microtubule-associated protein expressed in mature neurons, interacts with tubulin to promote the assembly and stabilization of microtubules. However, abnormally hyperphosphorylated tau dissociates from microtubules and self-aggregates. Tau aggregates,...
19.
Kim S, Chung H, Mai H, Nam Y, Shin S, Park Y, et al.
Int J Mol Sci . 2020 Jul; 21(12). PMID: 32630597
Alzheimer's disease (AD) is the most common type of dementia. AD involves major pathologies such as amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. During the progression of AD,...
20.
Park Y, Shin S, Kim H, Hong S, Kim S, Nam Y, et al.
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32486013
It has been reported that damage to the mitochondria affects the progression of Alzheimer's disease (AD), and that mitochondrial dysfunction is improved by omega-3. However, no animal or cell model...