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Sony George

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Articles 48
Citations 89
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Recent Articles
1.
Indongo G, Varghese S, Shkhair A, Abraham M, Rajeevan G, Kala A, et al.
Spectrochim Acta A Mol Biomol Spectrosc . 2025 Mar; 335:125981. PMID: 40054147
This study introduces a fluorescence turn-on sensor for the selective detection of valine, an amino acid increasingly recognized as a potential biomarker in cancer diagnostics, using iron(III) (Fe) quenched L-cysteine...
2.
Varghese S, Abraham M, Shkhair A, Indongo G, Rajeevan G, B K A, et al.
Anal Methods . 2025 Feb; 17(8):1850-1859. PMID: 39905843
Immunoassay techniques are widely recognized for their sensitivity and selectivity in biomarker detection; however, their high cost, time-consuming protocols and limited stability often pose significant limitations. In this study, we...
3.
Abraham M, Madanan A, Varghese S, Shkhair A, Indongo G, Rajeevan G, et al.
Anal Methods . 2025 Jan; 17(5):1125-1136. PMID: 39811969
The neuronal tau peptide serves as a key biomarker for neurodegenerative diseases, specifically, Alzheimer's disease, a condition that currently has no cure or definitive diagnosis. The methodology to noninvasively detect...
4.
Shkhair A, Madanan A, Varghese S, Abraham M, Indongo G, Rajeevan G, et al.
ACS Appl Bio Mater . 2024 Dec; 8(1):835-843. PMID: 39727303
Cardiovascular disease is the primary cause of mortality worldwide, as stated by the World Health Organization. We utilized the red fluorescence emitted by copper nanoclusters (CuNCs) to detect cardiac Troponin...
5.
Shkhair A, Madanan A, Varghese S, Abraham M, Indongo G, Rajeevan G, et al.
Spectrochim Acta A Mol Biomol Spectrosc . 2024 Dec; 329():125572. PMID: 39700550
Bilirubin is an important biomarker indicative of human health metabolism, especially in jaundice disease. In this work, we develop an Eu (Europium)-tungstate complex-based turn-off luminescence detection method for bilirubin in...
6.
Varghese S, Madanan A, Abraham M, Shkhair A, Indongo G, Rajeevan G, et al.
Analyst . 2024 Dec; 150(2):329-341. PMID: 39665509
Ischaemic stroke and glioma, as leading causes of mortality and long-term disability, pose critical challenges to healthcare systems, necessitating innovative approaches to enable early and cost-effective diagnosis for timely intervention....
7.
Kala A, Rajeevan G, Madanan A, Varghese S, Abraham M, Shkhair A, et al.
ACS Appl Bio Mater . 2024 Nov; 7(11):7700-7709. PMID: 39487038
An economical, rapid, and ultrasensitive detection of biomolecules in clinical settings is very crucial, particularly for the early detection of Cardiac Troponin I (cTnI), which is the gold standard biomarker...
8.
Indongo G, Madanan A, Varghese S, Shkhair A, Abraham M, Rajeevan G, et al.
ACS Appl Mater Interfaces . 2024 Oct; 16(45):61599-61608. PMID: 39475561
Sensing caspase-3 activity is essential for understanding the role of apoptosis in cancer dynamics, controlling therapeutic strategies, and improving patient care in cancer treatment. In this study, we demonstrate a...
9.
Varghese S, Madanan A, Abraham M, Shkhair A, Indongo G, Rajeevan G, et al.
Mikrochim Acta . 2024 Oct; 191(11):651. PMID: 39373729
A novel immunoassay platform is presented utilizing a cardiac troponin T antibody (Ab-cTnT) labelled with 5-carboxyfluorescein (5-FAM) integrated into a two-dimensional (2D) manganese dioxide nanosheet (MnO NS) matrix. This strategy...
10.
Madanan A, Varghese S, Abraham M, Shkhair A, Rajeevan G, Indongo G, et al.
Anal Methods . 2024 Sep; 16(40):6899-6906. PMID: 39279533
Fluorescence anisotropy (FA) is a versatile and efficient platform for developing biosensors that rely on the rate of rotations of fluorescence molecular entities in biochemical systems. However, by virtue of...