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Sonja Schoepflin

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Articles 10
Citations 591
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Recent Articles
1.
Ross A, Koepfli C, Schoepflin S, Timinao L, Siba P, Smith T, et al.
PLoS Negl Trop Dis . 2016 May; 10(5):e0004582. PMID: 27144482
Plasmodium vivax has the ability to relapse from dormant parasites in the liver weeks or months after inoculation, causing further blood-stage infection and potential onward transmission. Estimates of the force...
2.
Ross A, Koepfli C, Li X, Schoepflin S, Siba P, Mueller I, et al.
PLoS One . 2012 Sep; 7(8):e42496. PMID: 22952595
People living in endemic areas often habour several malaria infections at once. High-resolution genotyping can distinguish between infections by detecting the presence of different alleles at a polymorphic locus. However...
3.
Mueller I, Schoepflin S, Smith T, Benton K, Bretscher M, Lin E, et al.
Proc Natl Acad Sci U S A . 2012 Jun; 109(25):10030-5. PMID: 22665809
Genotyping Plasmodium falciparum parasites in longitudinal studies provides a robust approach to estimating force of infection (FOI) in the presence of superinfections. The molecular parameter (mol)FOI, defined as the number...
4.
Koepfli C, Schoepflin S, Bretscher M, Lin E, Kiniboro B, Zimmerman P, et al.
PLoS One . 2011 May; 6(4):e19010. PMID: 21552561
Background: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detection limit and, in...
5.
Mwingira F, Nkwengulila G, Schoepflin S, Sumari D, Beck H, Snounou G, et al.
Malar J . 2011 Apr; 10:79. PMID: 21470428
Background: The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order to capture late failures....
6.
Schoepflin S, Lin E, Kiniboro B, DaRe J, Mehlotra R, Zimmerman P, et al.
Am J Trop Med Hyg . 2010 Mar; 82(4):529-34. PMID: 20348494
A recent drug efficacy trial reported Coartem (artemether-lumefantrine) to be highly effective against Plasmodium falciparum in children less than 5 years of age in Papua New Guinea (PNG). In contrast,...
7.
Schoepflin S, Valsangiacomo F, Lin E, Kiniboro B, Mueller I, Felger I
Malar J . 2009 Nov; 8:250. PMID: 19878560
Background: The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater in...
8.
Stanisic D, Richards J, McCallum F, Michon P, King C, Schoepflin S, et al.
Infect Immun . 2009 Jan; 77(3):1165-74. PMID: 19139189
Substantial evidence indicates that antibodies to Plasmodium falciparum merozoite antigens play a role in protection from malaria, although the precise targets and mechanisms mediating immunity remain unclear. Different malaria antigens...
9.
Schoepflin S, Marfurt J, Goroti M, Baisor M, Mueller I, Felger I
Malar J . 2008 May; 7:78. PMID: 18460212
Background: The emergence of drug resistance is a major problem in malaria control. For mathematical modelling of the transmission and spread of drug resistance the determinant parameters need to be...
10.
Michon P, Cole-Tobian J, Dabod E, Schoepflin S, Igu J, Susapu M, et al.
Am J Trop Med Hyg . 2007 Jun; 76(6):997-1008. PMID: 17556601
In a treatment re-infection study of 206 Papua New Guinean school children, we examined risk of reinfection and symptomatic malaria caused by different Plasmodium species. Although children acquired a similar...