Songchang Chen
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Explore the profile of Songchang Chen including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
247
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Recent Articles
11.
Cao X, Chen S, Xu C
Am J Obstet Gynecol
. 2023 Feb;
228(6):763-764.
PMID: 36731818
No abstract available.
12.
Xu N, Shi W, Cao X, Zhou X, Jin L, Huang H, et al.
J Med Genet
. 2023 Jan;
60(9):910-917.
PMID: 36707240
Background: De novo mutations (DNMs) are linked with many severe early-onset disorders ranging from rare congenital malformation to intellectual disability. Conventionally, DNMs are considered to have an estimated recurrence rate...
13.
Zhang S, Pei Z, Lei C, Bai Y, Wu J, Xiao M, et al.
Clin Transl Med
. 2023 Jan;
13(1):e1160.
PMID: 36610059
No abstract available.
14.
Xu C, Li J, Chen S, Cai X, Jing R, Qin X, et al.
Cell Discov
. 2022 Oct;
8(1):109.
PMID: 36229437
Current non-invasive prenatal screening (NIPS) analyzes circulating fetal cell-free DNA (cfDNA) in maternal peripheral blood for selected aneuploidies or microdeletion/duplication syndromes. Many genetic disorders are refractory to NIPS largely because...
15.
Pan J, Li J, Chen S, Xu C, Huang H, Jin L
Front Genet
. 2022 Sep;
13:989041.
PMID: 36160002
Paternal sperm mosaicism has few consequences for fathers for mutations being restricted to sperm. However, it could potentially underlie severe sporadic disease in their offspring. Here, we present a live...
16.
Xu N, Zhou X, Shi W, Ye M, Cao X, Chen S, et al.
Front Physiol
. 2022 Aug;
13:893744.
PMID: 35991164
Recurrent pregnancy loss (RPL) is a major type of pathological pregnancy that still lacks reliable early diagnosis and effective treatment. The placenta is critical to fetal development and pregnancy success...
17.
Wu W, Zhou X, Jiang Z, Zhang D, Yu F, Zhang L, et al.
Hum Genomics
. 2022 Jul;
16(1):28.
PMID: 35897115
Background: High-cost, time-consuming and complex processes of several current approaches limit the use of noninvasive prenatal diagnosis (NIPD) for monogenic disorders in clinical application. Thus, a more cost-effective and easily...
18.
Zhou X, Shi W, Ye M, Chen S, Xu N, Xu C
Gene
. 2022 Feb;
819:146204.
PMID: 35101584
Substantial evidence now suggests an association between the FMR1 genotype and female fertility. The aim of this study was to determine whether a high normal FMR1 allele (35-54 repeats) affects...
19.
Chen S, Fei H, Zhang J, Chen Y, Huang H, Lu D, et al.
Front Mol Biosci
. 2021 Dec;
8:749842.
PMID: 34957211
The lifespan of Marfan Syndrome (MFS) patients is shortened, especially in patients without early diagnostics, preventive treatment, and elective surgery. Clinically, MFS diagnosis is mainly dependent on phenotypes, but for...
20.
Zhou X, Liu X, Shi W, Ye M, Chen S, Xu C
Front Endocrinol (Lausanne)
. 2021 Dec;
12:762976.
PMID: 34867804
An increasing number of studies have related the mitochondrial DNA (mtDNA) content to embryo viability and transfer outcomes. However, previous studies have focused more on the relationship between mtDNA and...