Somanath Bhat
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Explore the profile of Somanath Bhat including associated specialties, affiliations and a list of published articles.
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16
Citations
609
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Recent Articles
1.
Wilkin T, Hamilton N, Cawley A, Bhat S, Baoutina A
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473816
The term 'gene doping' is used to describe the use of any unauthorized gene therapy techniques. We developed a test for five likely candidate genes for equine gene doping: ,...
2.
Baoutina A, Bhat S, Li D, Emslie K
Drug Test Anal
. 2022 Nov;
15(3):314-323.
PMID: 36445200
Success in gene therapy in treating human disease makes this technology attractive to enhance athletic performance, creating the need for gene doping detection. In 2021, World Anti-Doping Agency (WADA) approved...
3.
Baoutina A, Bhat S
Gene Ther
. 2021 Aug;
29(7-8):425-430.
PMID: 34408285
Probe-based polymerase chain reaction (PCR), a popular method in genetic testing, could be prone to false positive or positively biased results if standards used for positive controls or as calibrants...
4.
Baoutina A, Bhat S, Partis L, Emslie K
Anal Chem
. 2019 Aug;
91(19):12268-12274.
PMID: 31465204
High accuracy, reliability, and reproducibility of genetic analyses in various applications require optimized and validated protocols and standards. Optimal procedures for storing the genetic material extracted from biological samples are...
5.
Bhat S, Emslie K
Biomol Detect Quantif
. 2016 Dec;
10:47-49.
PMID: 27990349
Accurate, reliable and reproducible quantification of nucleic acids (DNA/RNA) is important for many diagnostic applications and in routine laboratory testing, for example, for pathogen detection and detection of genetically modified...
6.
Yu X, Zheng W, Bhat S, Aquilina J, Zhang R
PeerJ
. 2015 Sep;
3:e1230.
PMID: 26355338
Bacillus sp. CDB3 possesses a novel eight-gene ars cluster (ars1, arsRYCDATorf7orf8) with some unusual features in regard to expression regulation. This study demonstrated that the cluster is a single operon...
7.
Burke D, Fu S, Forbes-Smith M, Bhat S, Partis L, Coldham T, et al.
Anal Bioanal Chem
. 2014 Jun;
406(26):6529-37.
PMID: 24948089
Hypermethylation at promoter regions of tumour suppressor genes is diagnostic for many cancers. Many genomic regions that may be the targets for clinical diagnostic assays have been identified through use...
8.
Burke D, Dong L, Bhat S, Forbes-Smith M, Fu S, Pinheiro L, et al.
Anal Chem
. 2012 Dec;
85(3):1657-64.
PMID: 23215355
Digital polymerase chain reaction (dPCR) is potentially a primary method for quantifying target DNA regions in a background of nontarget material and is independent of external calibrators. Accurate dPCR measurements...
9.
Bhat S, Polanowski A, Double M, Jarman S, Emslie K
PLoS One
. 2012 Jun;
7(6):e39181.
PMID: 22745712
Recent advances in nanofluidic technologies have enabled the use of Integrated Fluidic Circuits (IFCs) for high-throughput Single Nucleotide Polymorphism (SNP) genotyping (GT). In this study, we implemented and validated a...
10.
Pinheiro L, Coleman V, Hindson C, Herrmann J, Hindson B, Bhat S, et al.
Anal Chem
. 2011 Nov;
84(2):1003-11.
PMID: 22122760
Droplet digital polymerase chain reaction (ddPCR) is a new technology that was recently commercialized to enable the precise quantification of target nucleic acids in a sample. ddPCR measures absolute quantities...