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Sofie Snipstad

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Articles 35
Citations 361
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Recent Articles
1.
Einen C, Snipstad S, Wesche H, Nordlund V, Devold E, Amini N, et al.
J Control Release . 2024 Dec; 378:656-670. PMID: 39701458
The delivery of nanoparticles to tumors has been shown preclinically to be improved by microbubble-mediated ultrasound. However, the mechanisms and biological effects are not fully understood. In this study, we...
2.
Snipstad S, Einen C, Kastellet A, Fernandez J, Muhlenpfordt M, Kurbatskaya A, et al.
Ultrasound Med Biol . 2024 Oct; 51(1):33-42. PMID: 39389855
Objective: Ultrasound in combination with microbubbles can enhance accumulation and improve the distribution of various therapeutic agents in tumor tissue, leading to improved efficacy. Understanding the impact of treatment on...
3.
Nawijn C, Segers T, Lajoinie G, Berg S, Snipstad S, Davies C, et al.
Ultrasound Med Biol . 2024 Jun; 50(8):1099-1107. PMID: 38851940
Objective: Ultrasound-triggered bubble-mediated local drug delivery has shown potential to increase therapeutic efficacy and reduce systemic side effects, by loading drugs into the microbubble shell and triggering delivery of the...
4.
Snipstad S, Sulheim E, Aslund A, Hyldbakk A, Wagbo A, Klinkenberg G, et al.
Eur J Pharm Sci . 2024 May; 199:106804. PMID: 38763448
Lung cancer is one of the most common cancers and a leading cause of death, with poor prognosis and high unmet clinical need. Chemotherapy is a common part of the...
5.
Fernandez J, Snipstad S, Bjorkoy A, Davies C
Cells . 2024 Feb; 13(4. PMID: 38391962
Optimising drug delivery to tumours remains an obstacle to effective cancer treatment. A prerequisite for successful chemotherapy is that the drugs reach all tumour cells. The vascular network of tumours,...
6.
Fernandez J, Arbogen S, Sadeghinia M, Haram M, Snipstad S, Torp S, et al.
Cancers (Basel) . 2023 Nov; 15(22). PMID: 38001675
Pancreatic ductal adenocarcinoma (PDAC) remains a challenging malignancy, mainly due to its resistance to chemotherapy and its complex tumour microenvironment characterised by stromal desmoplasia. There is a need for new...
7.
Snipstad S, Bremnes F, Dehli Haugum M, Sulheim E
Cancer Med . 2023 Mar; 12(10):11589-11601. PMID: 36912188
Immunocompetent murine models are important tools for preclinical evaluation of immunotherapies. Here, six different immunocompetent tumor models based on four different cell lines were characterized, including metastatic lung cancer (CMT...
8.
Muhlenpfordt M, Olsen E, Kotopoulis S, Torp S, Snipstad S, Davies C, et al.
Ultrasound Med Biol . 2023 Mar; 49(5):1212-1226. PMID: 36858913
Objective: The blood-brain barrier (BBB) is an obstacle for cerebral drug delivery. Controlled permeabilization of the barrier by external stimuli can facilitate the delivery of drugs to the brain. Acoustic...
9.
Haram M, Snipstad S, Berg S, Mjones P, Ronne E, Lage J, et al.
Ultrasound Med Biol . 2023 Feb; 49(5):1275-1287. PMID: 36842903
Objective: Currently available cytotoxic treatments have limited effect on pancreatic ductal adenocarcinoma (PDAC) because desmoplastic stroma limits drug delivery. Efforts have been made to overcome these barriers by drug targeting...
10.
Hyldbakk A, Fleten K, Snipstad S, Aslund A, Davies C, Flatmark K, et al.
Nanomedicine . 2023 Jan; 48:102656. PMID: 36646195
Colorectal and ovarian cancers frequently develop peritoneal metastases with few treatment options. Intraperitoneal chemotherapy has shown promising therapeutic effects, but is limited by rapid drug clearance and systemic toxicity. We...