Sofia Toyra Silfversward
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Explore the profile of Sofia Toyra Silfversward including associated specialties, affiliations and a list of published articles.
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11
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102
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Recent Articles
1.
Erlandsson M, Malmhall-Bah E, Chandrasekaran V, Andersson K, Nilsson L, Toyra Silfversward S, et al.
Cells
. 2025 Jan;
13(24.
PMID: 39768214
Hyperinsulinemia connects obesity, and a poor lipid profile, with type 2 diabetes (T2D). Here, we investigated consequences of insulin exposure for T cell function in the canonical autoimmunity of rheumatoid...
2.
Lyngfelt L, Erlandsson M, Nadali M, Hedjazifar S, Pullerits R, Andersson K, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34067093
Adiposity is strongly associated with cardiovascular (CV) morbidity. Uncoupling protein 1 (UCP1) increases energy expenditure in adipocytes and may counteract adiposity. Our objective was to investigate a connection between expression...
3.
Nadali M, Lyngfelt L, Erlandsson M, Toyra Silfversward S, Andersson K, Bokarewa M, et al.
Front Med (Lausanne)
. 2021 Feb;
7:594622.
PMID: 33585503
Cardiovascular disease (CVD) causes premature mortality in rheumatoid arthritis (RA). Levels of soluble (s)RAGE change with aging, hypertension and hypercholesterolemia. We assessed whether sRAGE was associated with increased risk of...
4.
Wasen C, Ospelt C, Camponeschi A, Erlandsson M, Andersson K, Toyra Silfversward S, et al.
Front Immunol
. 2020 Aug;
11:1474.
PMID: 32765511
Smoking suppresses PD-1 expression in patients with rheumatoid arthritis (RA). In this study, we assess if smoking changed the epigenetic control over CD8 T cell memory formation through a microRNA...
5.
Erlandsson M, Lyngfelt L, Aberg N, Wasen C, Espino R, Toyra Silfversward S, et al.
BMC Med
. 2019 Jul;
17(1):141.
PMID: 31327319
Objectives: Since low insulin-like growth factor (IGF) 1 is often linked to inflammation, we analyze whether serum levels of IGF1 are associated with cardiovascular disease (CVD) in rheumatoid arthritis (RA)...
6.
Wasen C, Erlandsson M, Bossios A, Ekerljung L, Malmhall C, Toyra Silfversward S, et al.
Front Immunol
. 2018 Aug;
9:1677.
PMID: 30140263
Background: Smoking is a risk factor for developing rheumatoid arthritis (RA), but the mechanism remains uncertain. We previously demonstrated that smoking lowers the T cell activation threshold by limiting programmed...
7.
Nadali M, Pullerits R, Andersson K, Toyra Silfversward S, Erlandsson M, Bokarewa M
Int J Mol Sci
. 2017 Nov;
18(11).
PMID: 29137196
Despite the predominance of female patients and uncommon obesity, rheumatoid arthritis (RA) is tightly connected to increased cardiovascular morbidity. The aim of this study was to investigate transcriptional activity in...
8.
Erlandsson M, Toyra Silfversward S, Nadali M, Turkkila M, Svensson M, Jonsson I, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Jun;
1863(9):2158-2170.
PMID: 28583713
Background: Signalling through insulin-like growth factor 1 receptor (IGF-1R) is essential for cell survival, but may turn pathogenic in uncontrolled tissue growth in tumours. In rheumatoid arthritis (RA), the IGF-1R...
9.
Wasen C, Turkkila M, Bossios A, Erlandsson M, Andersson K, Ekerljung L, et al.
J Autoimmun
. 2017 Jan;
78:101-110.
PMID: 28082047
CD8 T cells have an emerging role in RA. Resent research indicates a causal relationship between the non-exhausted state of CD8 T cells, defined by lost function of PD-1, and...
10.
Andersson K, Turkkila M, Erlandsson M, Bossios A, Toyra Silfversward S, Hu D, et al.
Biochim Biophys Acta Mol Basis Dis
. 2016 Dec;
1863(3):663-673.
PMID: 27915033
MicroRNAs (miRs) represent a part of epigenetic control of autoimmunity gaining increasing attention in rheumatoid arthritis (RA). Since cigarette smoking plays important role in RA pathogenesis and reprograms transcriptional profile...