Sofia C Serra
Overview
Explore the profile of Sofia C Serra including associated specialties, affiliations and a list of published articles.
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14
Citations
310
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Recent Articles
1.
Campos J, Sampaio-Marques B, Santos D, Barata-Antunes S, Ribeiro M, Serra S, et al.
Tissue Eng Regen Med
. 2024 Nov;
22(1):113-128.
PMID: 39495459
Background: Priming strategies that improve the functionality of MSCs may be required to address issues limiting successful clinical translation of MSC therapies. For conditions requiring high trophic support such as...
2.
Lentilhas-Graca J, Santos D, Afonso J, Monteiro A, Pinho A, Mendes V, et al.
Front Immunol
. 2024 Mar;
15:1354479.
PMID: 38444856
Introduction: The inflammatory response after spinal cord injury (SCI) is an important contributor to secondary damage. Infiltrating macrophages can acquire a spectrum of activation states, however, the microenvironment at the...
3.
Mendes-Pinheiro B, Campos J, Marote A, Soares-Cunha C, Nickels S, Monzel A, et al.
Cells
. 2023 Nov;
12(21).
PMID: 37947643
Parkinson's disease (PD) is the most common movement disorder, characterized by the progressive loss of dopaminergic neurons from the nigrostriatal system. Currently, there is no treatment that retards disease progression...
4.
Pinho A, Cibrao J, Lima R, Gomes E, Serra S, Lentilhas-Graca J, et al.
Exp Neurol
. 2022 Jan;
351:113989.
PMID: 35065953
Adipose tissue derived stem cells (ASCs) are recognized to secret a myriad of molecules (secretome) know to modulate inflammatory response, promote axonal growth as well vascular remodeling and cellular survival....
5.
Campos J, Guerra-Gomes S, Serra S, Baltazar G, Oliveira J, Teixeira F, et al.
Brain Res
. 2020 Feb;
1732:146700.
PMID: 32032613
The central nervous system (CNS) has a limited auto-regeneration capacity, which makes it challenging for the development of new therapies. Previous studies from our lab have demonstrated the applicability of...
6.
Serra S, Costa J, Assuncao-Silva R, Teixeira F, Silva N, Anjo S, et al.
Biochimie
. 2018 Oct;
155:119-128.
PMID: 30342112
Mesenchymal stem cells (MSCs), and within them adipose tissue derived stem cells (ASCs), have been shown to have therapeutic effects on central nervous system (CNS) cell populations. Such effects have...
7.
Oliveira A, Anjo S, Vieira de Castro J, Serra S, Salgado A, Manadas B, et al.
Cell Commun Signal
. 2017 Oct;
15(1):37.
PMID: 28969644
Background: Glioblastoma (GBM), the most malignant primary brain tumor, leads to poor and unpredictable clinical outcomes. Recent studies showed the tumor microenvironment has a critical role in regulating tumor growth...
8.
Martins L, Costa R, Pedro J, Aguiar P, Serra S, Teixeira F, et al.
Sci Rep
. 2017 Jun;
7(1):4153.
PMID: 28646200
Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative medicine, with increasing importance in central and peripheral nervous system repair. However, MSCs grafting present disadvantages, such as,...
9.
Pires A, Teixeira F, Mendes-Pinheiro B, Serra S, Sousa N, Salgado A
Prog Neurobiol
. 2017 May;
156:69-89.
PMID: 28457671
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons and/or loss od neuronal projections, in several dopaminergic networks. Current treatments for idiopathic PD rely mainly...
10.
Teixeira F, Panchalingam K, Assuncao-Silva R, Serra S, Mendes-Pinheiro B, Patricio P, et al.
Sci Rep
. 2016 Jun;
6:27791.
PMID: 27301770
In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to their secretome. The...