Soetkin van Kerckhoven
Overview
Explore the profile of Soetkin van Kerckhoven including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
288
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Recent Articles
1.
Bolean M, Izzi B, van Kerckhoven S, Bottini M, Ramos A, Millan J, et al.
Biochim Biophys Acta Gen Subj
. 2020 May;
1864(8):129629.
PMID: 32360152
Backgound: Vascular smooth muscle cells (VSMCs) transdifferentiated ectopically trigger vascular calcifications, contributing to clinical cardiovascular disease in the aging population. AnxA5 and TNAP play a crucial role in (patho)physiological mineralization....
2.
Veloso T, Claes J, van Kerckhoven S, Ditkowski B, Hurtado-Aguilar L, Jockenhoevel S, et al.
J Thorac Cardiovasc Surg
. 2017 Jul;
155(1):325-332.e4.
PMID: 28712577
Background: Various conduits and stent-mounted valves are used as pulmonary valve graft tissues for right ventricular outflow tract reconstruction with good hemodynamic results. Valve replacement carries an increased risk of...
3.
Criel M, Izzi B, Vandenbriele C, Liesenborghs L, van Kerckhoven S, Lox M, et al.
Thromb Res
. 2016 Sep;
146:76-83.
PMID: 27614188
Background: Platelet Endothelial Aggregation Receptor-1 (PEAR1) is a transmembrane platelet receptor that amplifies the activation of the platelet fibrinogen receptor (αIIbβ3) during platelet aggregation. In man, Pear1 polymorphisms are associated...
4.
Vandenbriele C, Sun Y, Criel M, Cludts K, van Kerckhoven S, Izzi B, et al.
Platelets
. 2015 Dec;
27(4):365-72.
PMID: 26619766
Unlabelled: Dextran sulfate (DxS; Mr 500 kD) induces fibrinogen receptor (αIIbβ3) activation via CLEC-2/Syk signaling and via a Syk-independent SFK/PI3K/Akt-dependent tyrosine kinase pathway in human and murine platelets. The platelet...
5.
Hoylaerts M, van Kerckhoven S, Kiffer-Moreira T, Sheen C, Narisawa S, Millan J
PLoS One
. 2015 Mar;
10(3):e0119874.
PMID: 25775211
The conserved active site of alkaline phosphatases (AP) contains catalytically important Zn2+ (M1 and M2) and Mg2+-sites (M3) and a fourth peripheral Ca2+ site (M4) of unknown significance. We have...
6.
Luyts K, Smulders S, Napierska D, van Kerckhoven S, Poels K, Scheers H, et al.
Part Fibre Toxicol
. 2014 Nov;
11:61.
PMID: 25394423
Background: Pulmonary exposure to nanoparticles (NPs) may affect, in addition to pulmonary toxicity, the cardiovascular system such as procoagulant effects, vascular dysfunction and progression of atherosclerosis. However, only few studies...
7.
Emmerechts J, De Vooght V, Haenen S, Loyen S, van Kerckhoven S, Hemmeryckx B, et al.
Thromb Haemost
. 2012 Aug;
108(4):756-68.
PMID: 22872007
Epidemiological studies indicate that elderly persons are particularly susceptible to the cardiovascular health complications of air pollution, but pathophysiological mechanisms behind the increased susceptibility remain unclear. Therefore, we investigated how...
8.
Peeters K, Loyen S, van Kerckhoven S, Stoffels K, Hoylaerts M, Van Geet C, et al.
Br J Haematol
. 2010 Aug;
151(1):54-61.
PMID: 20735399
Megakaryocytes and platelets express the stimulatory G protein (Gs)-coupled VPAC1 receptor, for which the pituitary adenylyl cyclase-activating peptide (PACAP) and vasoactive intestinal peptide (VIP) are agonists. The neuropeptide PACAP and...
9.
Meijers B, van Kerckhoven S, Verbeke K, Dehaen W, Vanrenterghem Y, Hoylaerts M, et al.
Am J Kidney Dis
. 2009 Jul;
54(5):891-901.
PMID: 19615803
Background: Cardiovascular disease is highly prevalent in patients with chronic kidney disease. In hemodialysis patients, the protein-bound uremic retention solute p-cresol is independently associated with cardiovascular disease. The underlying mechanisms...
10.
Moura R, Tjwa M, Vandervoort P, van Kerckhoven S, Holvoet P, Hoylaerts M
Circ Res
. 2008 Sep;
103(10):1181-9.
PMID: 18818405
Thrombospondin (TSP)1 is implicated in various inflammatory processes, but its role in atherosclerotic plaque formation and progression is unclear. Therefore, the development of atherosclerosis was compared in ApoE(-/-) and Tsp1(-/-)ApoE(-/-)...