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Soek-Ying Neo

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Articles 11
Citations 890
Followers 0
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Recent Articles
1.
Xiang W, Sng C, Lam Y, Kok Z, Linn Y, Neo S, et al.
Int J Mol Sci . 2024 Jul; 25(14). PMID: 39063200
While BCR::ABL1 tyrosine kinase inhibitors have transformed the treatment paradigm for chronic myeloid leukemia (CML), disease progression and treatment resistance due to BCR::ABL1-dependent and BCR::ABL1-independent mechanisms remain a therapeutic challenge....
2.
Neo S, Siew Y, Yew H, He Y, Poh K, Tsai Y, et al.
BMC Complement Med Ther . 2023 Mar; 23(1):79. PMID: 36899361
Background: The rich biodiversity of medicinal plants and their importance as sources of novel therapeutics and lead compounds warrant further research. Despite advances in debulking surgery and chemotherapy, the risks...
3.
Wee H, Neo S, Singh D, Yew H, Qiu Z, Tsai X, et al.
BMC Complement Med Ther . 2020 Mar; 20(1):91. PMID: 32188443
Background: Dysregulation of pro-inflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) form the basis of immune-mediated inflammatory diseases. Vitex trifolia L. is a medicinal plant growing in...
4.
Singh D, Siew Y, Chong T, Yew H, Ho S, Lim C, et al.
Molecules . 2019 Feb; 24(4). PMID: 30781458
(Vitaceae) is a Southeast Asian medicinal plant. In this study, an ethyl acetate fraction of leaves was studied for its phytoconstituents using high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-microTOF-Q-MS/MS) analysis. A...
5.
Siew Y, Yew H, Neo S, Seow S, Lew S, Lim S, et al.
J Ethnopharmacol . 2019 Jan; 235:75-87. PMID: 30599223
Ethnopharmacological Relevance: The extensive biodiversity of plants in Southeast Asia and inadequate research hitherto warrant a continued investigation into medicinal plants. On the basis of a careful review of fresh...
6.
Siew Y, Neo S, Yew H, Lim S, Ng Y, Lew S, et al.
Int Immunol . 2015 Jul; 27(12):621-32. PMID: 26138671
Selected cytotoxic chemicals can provoke the immune system to recognize and destroy malignant tumors. Most of the studies on immunogenic cell death are focused on the signals that operate on...
7.
Siew Y, Zareisedehizadeh S, Seetoh W, Neo S, Tan C, Koh H
J Ethnopharmacol . 2014 Jul; 155(3):1450-66. PMID: 25058874
Ethnopharmacological Relevance: The use of medicinal plants in human health has been documented since ancient times and they provide a useful source of new therapeutics. In Singapore, despite the accessibility...
8.
Toh D, Patel D, Chan E, Teo A, Neo S, Koh H
Chin Med . 2011 Jan; 6:4. PMID: 21255464
Background: Panax notoginseng is a potential source of anticancer compounds. This study aims to investigate the effects of steaming on the chemical profile of P. notoginseng and the anti-proliferative effects...
9.
Ng S, Neo S, Yap Y, Karuturi R, Loh E, Liau K, et al.
Biochem Biophys Res Commun . 2009 Jul; 387(2):310-5. PMID: 19591801
Cancer such as hepatocellular carcinoma (HCC) is characterized by complex perturbations in multiple signaling pathways, including the phosphoinositide-3-kinase (PI3K/AKT) pathways. Herein we investigated the role of PI3K catalytic isoforms, particularly...
10.
Ng L, Hibberd M, Ooi E, Tang K, Neo S, Tan J, et al.
BMC Infect Dis . 2004 Sep; 4:34. PMID: 15357874
Background: The molecular basis of severe acute respiratory syndrome (SARS) coronavirus (CoV) induced pathology is still largely unclear. Many SARS patients suffer respiratory distress brought on by interstitial infiltration and...