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Smriti Chadha

Explore the profile of Smriti Chadha including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 11
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Recent Articles
1.
Hary A, Chadha S, Mercaldo N, Smith E, van der Kouwe A, Fischl B, et al.
Acta Neuropathol Commun . 2025 Feb; 13(1):44. PMID: 40022196
The locus coeruleus (LC) has been identified as a site that develops phosphorylated tau pathology earlier than cerebral cortex. We present data using high-resolution postmortem MRI and validated tau histopathology...
2.
Khalil M, Wang J, Yang C, Vu L, Yin C, Chadha S, et al.
bioRxiv . 2024 Dec; PMID: 39677690
One Sentence Summary: Targeting MARCHF8 restores MHC-I proteins, induces antitumor CD8 T cell activity, and suppresses the growth of ICI-refractory tumors.
3.
Khalil M, Yang C, Vu L, Chadha S, Nabors H, James C, et al.
J Virol . 2024 Jan; 98(2):e0172623. PMID: 38226814
The human papillomavirus (HPV) oncoprotein E7 is a relatively short-lived protein required for HPV-driven cancer development and maintenance. E7 is degraded through ubiquitination mediated by cullin 1 (CUL1) and the...
4.
Khalil M, Yang C, Vu L, Chadha S, Nabors H, James C, et al.
bioRxiv . 2023 Nov; PMID: 37961092
The human papillomavirus (HPV) oncoprotein E7 is a relatively short-lived protein required for HPV-driven cancer development and maintenance. E7 is degraded through ubiquitination mediated by cullin 1 (CUL1) and the...
5.
Khalil M, Yang C, Vu L, Chadha S, Nabors H, Welbon C, et al.
PLoS Pathog . 2023 Mar; 19(3):e1011171. PMID: 36867660
The membrane-associated RING-CH-type finger ubiquitin ligase MARCHF8 is a human homolog of the viral ubiquitin ligases Kaposi's sarcoma herpesvirus K3 and K5 that promote host immune evasion. Previous studies have...