Smita Krishnaswamy
Overview
Explore the profile of Smita Krishnaswamy including associated specialties, affiliations and a list of published articles.
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75
Citations
3859
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Recent Articles
1.
Fagerberg E, Attanasio J, Dien C, Singh J, Kessler E, Abdullah L, et al.
Science
. 2025 Feb;
387(6735):eadn2337.
PMID: 39946463
Naïve CD8 T cells have the potential to differentiate into a spectrum of functional states during an immune response. How these developmental decisions are made and what mechanisms exist to...
2.
Venkat A, Leone S, Youlten S, Fagerberg E, Attanasio J, Joshi N, et al.
Nat Comput Sci
. 2024 Dec;
4(12):955-977.
PMID: 39706866
In single-cell sequencing analysis, several computational methods have been developed to map the cellular state space, but little has been done to map or create embeddings of the gene space....
3.
Garcia C, Venkat A, McQuaid D, Agabiti S, Tong A, Cardone R, et al.
bioRxiv
. 2024 Dec;
PMID: 39677599
Pancreatic endocrine-exocrine crosstalk plays a key role in normal physiology and disease. For instance, endocrine islet beta (β) cell secretion of insulin or cholecystokinin (CCK) promotes progression of pancreatic adenocarcinoma...
4.
Zapatero M, Tong A, Opzoomer J, OSullivan R, Cardoso Rodriguez F, Sufi J, et al.
Cell
. 2024 Nov;
187(25):7335-7349.
PMID: 39603238
No abstract available.
5.
Singh R, Zhang Y, Bhaskar D, Srihari V, Tek C, Zhang X, et al.
bioRxiv
. 2024 Nov;
PMID: 39574662
Schizophrenia is a severe psychiatric disorder associated with a wide range of cognitive and neurophysiological dysfunctions and long-term social difficulties. In this paper, we test the hypothesis that integration of...
6.
Koonce N, Emerson S, Bhaskar D, Kuchroo M, Moyle M, Arroyo-Morales P, et al.
bioRxiv
. 2024 Nov;
PMID: 39484462
Volume electron microscopy (vEM) datasets such as those generated for connectome studies allow nanoscale quantifications and comparisons of the cell biological features underpinning circuit architectures. Quantifications of cell biological relationships...
7.
Sun X, Xu C, Rocha J, Liu C, Hollander-Bodie B, Goldman L, et al.
ArXiv
. 2024 Sep;
PMID: 39314512
In many data-driven applications, higher-order relationships among multiple objects are essential in capturing complex interactions. Hypergraphs, which generalize graphs by allowing edges to connect any number of nodes, provide a...
8.
Venkat A, Carlino M, Lawton B, Prasad M, Amodio M, Gibson C, et al.
Genome Res
. 2024 Jul;
34(6):837-850.
PMID: 38977309
Studies on human parathyroids are generally limited to hyperfunctioning glands owing to the difficulty in obtaining normal human tissue. We therefore obtained non-human primate (NHP) parathyroids to provide a suitable...
9.
Youlten S, Miao L, Hoppe C, Boswell C, Musaev D, Abdelmessih M, et al.
bioRxiv
. 2024 May;
PMID: 38798464
The capacity for embryonic cells to differentiate relies on a large-scale reprogramming of the oocyte and sperm nucleus into a transient totipotent state. In zebrafish, this reprogramming step is achieved...
10.
Hodgson L, Li Y, Iturria-Medina Y, Stratton J, Wolf G, Krishnaswamy S, et al.
Commun Biol
. 2024 May;
7(1):591.
PMID: 38760483
Late onset Alzheimer's disease (AD) is a progressive neurodegenerative disease, with brain changes beginning years before symptoms surface. AD is characterized by neuronal loss, the classic feature of the disease...