Slavko Pecar
Overview
Explore the profile of Slavko Pecar including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
94
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Recent Articles
1.
Frlan R, Kovac A, Blanot D, Gobec S, Pecar S, Obreza A
Acta Chim Slov
. 2013 Sep;
58(2):295-310.
PMID: 24062040
Mur ligases are essential enzymes involved in the cytoplasmic steps of peptidoglycan synthesis which remain attractive, yet unexploited targets. In order to develop new antibacterial agents, we have designed a...
2.
Plajnsek K, Pajk S, Govedarica B, Pecar S, Srcic S, Kristl J
Int J Pharm
. 2011 Jul;
416(1):384-93.
PMID: 21745558
To improve visualization of nanoparticles within the cells' compartments, we synthesized a coumarin based fluorescent derivative, tetradecyl diethylamino coumarin amid, 14-DACA. In this compound the coumarin chromophore is linked with...
3.
Pajk S, Garvas M, Strancar J, Pecar S
Org Biomol Chem
. 2011 Apr;
9(11):4150-9.
PMID: 21505664
A serious drawback of ESR, particularly in its application to cells, is the lack of information on the location of spin probes in the system. In order to realize real...
4.
Lahajnar G, Sobotic B, Sepe A, Jazbinsek V, Pecar S
Gen Physiol Biophys
. 2010 Dec;
29(4):373-80.
PMID: 21157000
Sodium nitroprusside (SNP) is a nitric oxide (•NO) donor in vitro and in vivo. In this paper the time variation of the intracellular water proton nuclear magnetic resonance (NMR) effective...
5.
Sink R, Gobec S, Pecar S, Zega A
Curr Med Chem
. 2010 Oct;
17(34):4231-55.
PMID: 20939815
High-throughput screening (HTS) is one of the most powerful approaches available for identifying new lead compounds for the growing catalogue of validated drug targets. However, just as virtual and experimental...
6.
Gosenca M, Obreza A, Pecar S, Gasperlin M
AAPS PharmSciTech
. 2010 Sep;
11(3):1485-92.
PMID: 20845090
The aim of this work was to test innovative approach for enhancing ascorbyl palmitate stability in microemulsions for topical application by addition of newly synthesized co-antioxidant 4-(tridecyloxy)benzaldehyde oxime (TDBO) and...
7.
Peitl P, Tomse P, Kroselj M, Socan A, Hojker S, Pecar S, et al.
Nucl Med Commun
. 2009 Jul;
30(10):807-14.
PMID: 19623093
Objective: Yttrium-90 (Y)-labelled peptides such as DOTATOC and antibodies such as Zevalin are widely used in radionuclide therapy. Indium-111 (In) is used as a Y surrogate for imaging and dosimetry...
8.
Dejanovic B, Mirosavljevic K, Noethig-Laslo V, Pecar S, Sentjurc M, Walde P
Chem Phys Lipids
. 2008 Oct;
156(1-2):17-25.
PMID: 18835261
Aqueous decanoic acid/sodium decanaote systems were studied as a function of pH and concentration, up to 0.3 M decanoic acid/sodium decanoate, by electron spin resonance (ESR) spectroscopy using three different...
9.
Frlan R, Kovac A, Blanot D, Gobec S, Pecar S, Obreza A
Molecules
. 2008 Feb;
13(1):11-30.
PMID: 18259126
A series of novel N-benzylidenesulfonohydrazide compounds were designed and synthesized as inhibitors of UDP-N-acetylmuramic acid: L-alanine ligase (MurC) and UDP-N-acetylmuramoyl-L-alanine: D-glutamate ligase (MurD) from E. coli, involved in the biosynthesis...
10.
Mravljak J, Konc J, Hodos Ccaron Ek M, Solmajer T, Pecar S
J Phys Chem B
. 2006 Dec;
110(51):25559-61.
PMID: 17181183
Molecular dynamics simulation has been performed to investigate the structural properties of perifosine and its synthetic spin-labeled alkylphospholipid analogues. The conformations adopted by these compounds in water and in a...