Sivan Izraely
Overview
Explore the profile of Sivan Izraely including associated specialties, affiliations and a list of published articles.
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24
Citations
577
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Recent Articles
1.
Levy O, Altaras A, Binyamini L, Sagi-Assif O, Izraely S, Cooks T, et al.
Cancers (Basel)
. 2024 Nov;
16(22).
PMID: 39594759
: In this study, for the first time, we examined and compared the sensitivity of four patient-derived cutaneous melanoma cell lines to alpha radiation in vitro and analyzed it in...
2.
Adir O, Sagi-Assif O, Meshel T, Ben-Menachem S, Pasmanik-Chor M, Hoon D, et al.
Cancers (Basel)
. 2023 Oct;
15(20).
PMID: 37894348
Reciprocal signaling between melanoma brain metastatic (MBM) cells and microglia reprograms the phenotype of both interaction partners, including upregulation of the transcription factor JunB in microglia. Here, we aimed to...
3.
Chelladurai M, Xu D, Izraely S, Ben-Menachem S, Bengaiev R, Sagi-Assif O, et al.
Int J Cancer
. 2023 Sep;
154(3):561-572.
PMID: 37675956
Metastatic (as well as tumor) microenvironments contain both cancer-promoting and cancer-restraining factors. The balance between these opposing forces determines the fate of cancer cells that disseminate to secondary organ sites....
4.
Izraely S, Ben-Menachem S, Malka S, Sagi-Assif O, Bustos M, Adir O, et al.
Cells
. 2023 Jun;
12(11).
PMID: 37296634
Previous studies from our lab demonstrated that the crosstalk between brain-metastasizing melanoma cells and microglia, the macrophage-like cells of the central nervous system, fuels progression to metastasis. In the present...
5.
De Las Rivas J, Brozovic A, Izraely S, Casas-Pais A, Witz I, Figueroa A
Arch Toxicol
. 2021 May;
95(7):2279-2297.
PMID: 34003341
Over the last decade, important clinical benefits have been achieved in cancer patients by using drug-targeting strategies. Nevertheless, drug resistance is still a major problem in most cancer therapies. Epithelial-mesenchymal...
6.
Leong S, Witz I, Sagi-Assif O, Izraely S, Sleeman J, Piening B, et al.
Clin Exp Metastasis
. 2021 May;
39(1):85-99.
PMID: 33970362
Cancer heterogeneity is a result of genetic mutations within the cancer cells. Their proliferation is not only driven by autocrine functions but also under the influence of cancer microenvironment, which...
7.
Izraely S, Ben-Menachem S, Sagi-Assif O, Meshel T, Malka S, Telerman A, et al.
Mol Oncol
. 2020 Dec;
15(5):1376-1390.
PMID: 33274599
Previous studies indicated that microglia cells upregulate the expression of aldolase C (ALDOC) in melanoma cells. The present study using brain-metastasizing variants from three human melanomas explores the functional role...
8.
Izraely S, Witz I
Int J Cancer
. 2020 Aug;
148(6):1308-1322.
PMID: 32761606
The conclusion derived from the information provided in this review is that disseminating tumor cells (DTC) collaborate with the microenvironment of a future metastatic organ site in the establishment of...
9.
Moshe A, Izraely S, Sagi-Assif O, Malka S, Ben-Menachem S, Meshel T, et al.
Cells
. 2020 Jul;
9(7).
PMID: 32668704
Granulocyte-monocyte colony stimulating factor (GM-CSF) is used as an adjuvant in various clinical and preclinical studies with contradictory results. These were attributed to opposing effects of GM-CSF on the immune...
10.
Ramos R, Bustos M, Wu J, Jones P, Chang S, Kiyohara E, et al.
Mol Oncol
. 2020 May;
14(8):1760-1778.
PMID: 32358995
Melanoma metastasis to the brain is one of the most frequent extracranial brain tumors. Cell surface gangliosides are elevated in melanoma metastasis; however, the metabolic regulatory mechanisms that govern these...