Siva Singothu
Overview
Explore the profile of Siva Singothu including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
25
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0
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Recent Articles
1.
Brahma U, Singothu S, Suresh A, Vemula D, Munagalasetty S, Sharma P, et al.
J Appl Microbiol
. 2024 Oct;
135(11).
PMID: 39474886
Aims: Staphylococcus aureus, a high-priority pathogen proclaimed to cause infections ranging from mild to life-threatening, presents significant challenges in treatment. New therapies can be developed quicker using open drug discovery...
2.
Sandeep Chary P, Bansode A, Rajana N, Bhavana V, Singothu S, Sharma A, et al.
Int J Pharm
. 2024 Apr;
657:124109.
PMID: 38626846
Breast cancer continues to pose a substantial global health challenge, emphasizing the critical need for the advancement of novel therapeutic approaches. Key players in the regulation of apoptosis, a fundamental...
3.
Singh S, Varshney N, Singothu S, Bhandari V, Jha H
Environ Pollut
. 2024 Mar;
347:123676.
PMID: 38442821
Organochlorine (OC) and organophosphorus (OP) pesticides such as chlorpyrifos (CPF) and endosulfan (ES) have been associated with a plethora of adverse health effects. Helicobacter pylori (H. pylori) infection can lead...
4.
Kamble S, Singh S, Suresh A, Singothu S, Dandesena D, Bhandari V, et al.
Microbiol Spectr
. 2024 Feb;
12(4):e0325823.
PMID: 38421193
The growing emergence of resistance to current anti-theilerial agents necessitates the exploration of alternative approaches to drug discovery. This study evaluated the antiparasitic efficacy of 148 compounds derived from an...
5.
Singothu S, Bhandari V
J Biomol Struct Dyn
. 2024 Feb;
:1-15.
PMID: 38379380
The Quorum Sensing (QS) system in bacteria has become a focal point for researchers aiming to develop novel antimicrobials to combat multidrug-resistant bacteria. , an opportunistic Gram-negative bacterium, has developed...
6.
Patil S, Sandeep Chary P, Maddipatla S, Madhavi Y, Singothu S, Bhandari V, et al.
J Biomol Struct Dyn
. 2024 Jan;
:1-18.
PMID: 38247232
Cyclodextrin complexes loaded with venetoclax for improved solubility and therapeutic efficacy as repurposed drug. The venetoclax-cyclodextrin inclusion complex was prepared using kneading method. Primarily in-silico molecular docking study was performed...
7.
Singothu S, Devsani N, Jahidha Begum P, Maddi D, Bhandari V
J Biomol Struct Dyn
. 2023 Aug;
42(17):9064-9075.
PMID: 37646649
Emerging antimicrobial resistance has highlighted the need to design more effective antibiotics to treat deadly bacterial infections. s outer membrane protein A (OmpA) is a critical virulence component involved in...
8.
Singothu S, Begum P, Maddi D, Devsani N, Bhandari V
J Cell Biochem
. 2023 Aug;
124(10):1573-1586.
PMID: 37642215
Antimicrobial resistance (AMR) poses a significant threat to global public health, with multidrug-resistant Pseudomonas aeruginosa being a leading cause of mortality, accounting for 18%-61% of deaths annually. The quorum sensing...
9.
Podduturi S, Vemula D, Singothu S, Bhandari V
J Biomol Struct Dyn
. 2023 Aug;
42(16):8242-8255.
PMID: 37555596
The re-emergence of the monkeypox virus (MPXV) in 2022 has become a global issue. The virus was first found in Denmark in 1958. The first human MPXV disease was reported...
10.
Kumar R, T A, Singothu S, Singh S, Bhandari V
Biomed Pharmacother
. 2022 Jan;
147:112656.
PMID: 35091238
Mitochondrial uncoupling proteins (UCP) are a part of the large family of mitochondrial solute carriers (SLC25s), concentrated in the inner mitochondrial membrane that carries protons from intermembrane space to the...