Siu Sylvia Lee
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Explore the profile of Siu Sylvia Lee including associated specialties, affiliations and a list of published articles.
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44
Citations
2329
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Recent Articles
1.
Fox B, Helf M, Burkhardt R, Artyukhin A, Curtis B, Fajardo Palomino D, et al.
Nat Commun
. 2024 Jul;
15(1):6090.
PMID: 39030188
No abstract available.
2.
Emerson F, Chiu C, Lin L, Riedel C, Zhu M, Lee S
Nat Commun
. 2024 Mar;
15(1):2320.
PMID: 38485937
SET-26, HCF-1, and HDA-1 are highly conserved chromatin factors with key roles in development and aging. Here we present mechanistic insights into how these factors regulate gene expression and modulate...
3.
Fox B, Helf M, Burkhardt R, Artyukhin A, Curtis B, Fajardo Palomino D, et al.
Nat Commun
. 2024 Feb;
15(1):1520.
PMID: 38374083
Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression,...
4.
Emerson F, Lee S
Front Mol Biosci
. 2023 Oct;
10:1270285.
PMID: 37877123
Aging affects nearly all aspects of our cells, from our DNA to our proteins to how our cells handle stress and communicate with each other. Age-related chromatin changes are of...
5.
Fox B, Helf M, Burkhardt R, Artyukhin A, Curtis B, Fajardo Palomino D, et al.
bioRxiv
. 2023 Sep;
PMID: 37693574
Fatty acid desaturation is central to metazoan lipid metabolism and provides building blocks of membrane lipids and precursors of diverse signaling molecules. Nutritional conditions and associated microbiota regulate desaturase expression,...
6.
Chaturbedi A, Lee S
bioRxiv
. 2023 Jul;
PMID: 37398385
Curtailed reproduction affects lifespan and fat metabolism in diverse organisms, suggesting a regulatory axis between these processes. In ablation of germline stem cells (GSCs) leads to extended lifespan and increased...
7.
Emerson F, Chiu C, Lin L, Riedel C, Zhu M, Lee S
bioRxiv
. 2023 Mar;
PMID: 36993207
SET-26, HCF-1, and HDA-1 are highly conserved chromatin factors with key roles in development and aging. Here we present mechanistic insights into how these factors regulate gene expression and modulate...
8.
Burkhardt R, Artyukhin A, Aprison E, Curtis B, Fox B, Ludewig A, et al.
Nat Commun
. 2023 Jan;
14(1):320.
PMID: 36658169
Recent studies of animal metabolism have revealed large numbers of novel metabolites that are involved in all aspects of organismal biology, but it is unclear to what extent metabolomes differ...
9.
Emerson F, Lee S
Curr Protoc
. 2022 Jun;
2(6):e445.
PMID: 35714350
Cleavage under targets and release using nuclease (CUT&RUN) is a recently developed chromatin profiling technique that uses a targeted micrococcal nuclease cleavage strategy to obtain high-resolution binding profiles of protein...
10.
Li C, Pu M, Wang W, Chaturbedi A, Emerson F, Lee S
PLoS Genet
. 2021 Sep;
17(9):e1009432.
PMID: 34506495
Epigenetic alterations occur as organisms age, and lead to chromatin deterioration, loss of transcriptional silencing and genomic instability. Dysregulation of the epigenome has been associated with increased susceptibility to age-related...