Siobhan C Wade
Overview
Explore the profile of Siobhan C Wade including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
160
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0
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Recent Articles
1.
Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function
OBrien A, Hanlon M, Marzaioli V, Wade S, Flynn K, Fearon U, et al.
Front Immunol
. 2021 Jul;
12:672461.
PMID: 34248953
Objectives: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. Janus Kinase inhibitors (JAKi) have emerged as an encouraging class of drugs for the treatment of PsA. Here,...
2.
Marzaioli V, Canavan M, Floudas A, Wade S, Low C, Veale D, et al.
Front Immunol
. 2020 Aug;
11:1406.
PMID: 32733468
Monocyte-derived Dendritic cells (Mo-DC) are a distinct DC subset, involved in inflammation and infection, they originate from monocytes upon stimulation in the circulation and their activation and function may vary...
3.
Serum MicroRNA Signature as a Diagnostic and Therapeutic Marker in Patients with Psoriatic Arthritis
Wade S, McGarry T, Wade S, Fearon U, Veale D
J Rheumatol
. 2020 Mar;
47(12):1760-1767.
PMID: 32115427
Objective: MicroRNA (miRNA) are small endogenous regulatory RNA molecules that have emerged as potential therapeutic targets and biomarkers in autoimmunity. Here, we investigated serum miRNA levels in patients with psoriatic...
4.
Wade S, Canavan M, McGarry T, Low C, Wade S, Mullan R, et al.
Ann Rheum Dis
. 2019 Jan;
78(3):350-354.
PMID: 30626658
Objective: This study examines polyfunctional T-cells in psoriatic arthritis (PsA) synovial tissue and their associations with clinical disease and implications for therapy. Methods: PsA synovial tissue was enzymatically/mechanically digested to...
5.
Wade S, Trenkmann M, McGarry T, Canavan M, Marzaioli V, Wade S, et al.
J Autoimmun
. 2018 Sep;
96:86-93.
PMID: 30181004
Objectives: To investigate the functional role of miR-23a in synovial fibroblasts (SFC) activation in psoriatic arthritis (PsA). Methods: Differential expression of the miR-23a-27a-24-2 cluster was identified by real-time quantitative PCR...
6.
Katarzyna Oficjalska , Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, et al.
J Immunol
. 2014 Dec;
194(3):1252-60.
PMID: 25548224
Activation of the noncanonical inflammasome, mediated by caspase-11, serves as an additional pathway for the production of the proinflammatory cytokines IL-1β and IL-18. Noncanonical inflammasome activity occurs during host defense...