Sinead M ODonovan
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Explore the profile of Sinead M ODonovan including associated specialties, affiliations and a list of published articles.
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46
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581
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Recent Articles
11.
Valeri J, Stiplosek C, ODonovan S, Sinclair D, Grant K, Bollavarapu R, et al.
medRxiv
. 2023 Sep;
PMID: 37732207
Contextual triggers are significant factors contributing to relapse in substance use disorders (SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as mediators of reward memories....
12.
Alnafisah R, Lundh A, Asah S, Hoeflinger J, Wolfinger A, Hamoud A, et al.
Schizophrenia (Heidelb)
. 2022 Nov;
8(1):96.
PMID: 36376358
ATP functions as a neurotransmitter, acting on the ubiquitously expressed family of purinergic P2 receptors. In schizophrenia (SCZ), the pathways that modulate extracellular ATP and its catabolism to adenosine are...
13.
Zhang X, Wolfinger A, Wu X, Alnafisah R, Imami A, Hamoud A, et al.
Cells
. 2022 Oct;
11(20).
PMID: 36291180
Astrocytes have many important functions in the brain, but their roles in psychiatric disorders and their responses to psychotropic medications are still being elucidated. Here, we used gene enrichment analysis...
14.
Hamoud A, Bach K, Kakrecha O, Henkel N, Wu X, McCullumsmith R, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36233136
For over a century, a complex relationship between schizophrenia diagnosis and development of many cancers has been observed. Findings from epidemiological studies are mixed, with reports of increased, reduced, or...
15.
Valeri J, ODonovan S, Wang W, Sinclair D, Bollavarapu R, Gisabella B, et al.
Front Neurosci
. 2022 Sep;
16:903941.
PMID: 36161151
Substance use disorders are a debilitating group of psychiatric disorders with a high degree of comorbidity with major depressive disorder. Sleep and circadian rhythm disturbances are commonly reported in people...
16.
Alnafisah R, Reigle J, Eladawi M, ODonovan S, Funk A, Meller J, et al.
Neuropsychopharmacology
. 2022 Mar;
47(12):2033-2041.
PMID: 35354897
Antipsychotic drugs (APDs) are effective in treating positive symptoms of schizophrenia (SCZ). However, they have a substantial impact on postmortem studies. As most cohorts lack samples from drug-naive patients, many...
17.
Henkel N, Wu X, ODonovan S, Devine E, Jiron J, Rowland L, et al.
Mol Psychiatry
. 2022 Mar;
27(5):2393-2404.
PMID: 35264726
A substantial and diverse body of literature suggests that the pathophysiology of schizophrenia is related to deficits of bioenergetic function. While antipsychotics are an effective therapy for the management of...
18.
Alganem K, Hamoud A, Creeden J, Henkel N, Imami A, Joyce A, et al.
Curr Opin Pharmacol
. 2021 Dec;
62:117-129.
PMID: 34968947
Biological regulatory networks are dynamic, intertwined, and complex systems making them challenging to study. While quantitative measurements of transcripts and proteins are key to investigate the state of a biological...
19.
ODonovan S, McCullumsmith R, Shukla R
Curr Opin Pharmacol
. 2021 Dec;
62:82-84.
PMID: 34942403
No abstract available.
20.
Zhang X, Alnafisah R, Hamoud A, Shukla R, McCullumsmith R, ODonovan S
Adv Neurobiol
. 2021 Dec;
26:153-172.
PMID: 34888835
Glial cell types in the central nervous system (CNS) include microglia, oligodendrocytes and the most diverse type, astrocytes. Clinical and experimental evidence suggest critical roles for astrocytes in the pathogenesis...