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Simone Queiroz Pantaleao

Explore the profile of Simone Queiroz Pantaleao including associated specialties, affiliations and a list of published articles. Areas
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Citations 21
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Recent Articles
1.
Pantaleao S, Camillo L, Neves T, Menezes I, Stangherlin L, Batista H, et al.
PLoS One . 2023 Nov; 18(11):e0295457. PMID: 38033121
[This corrects the article DOI: 10.1371/journal.pone.0277953.].
2.
Correa Verissimo G, Pantaleao S, Fernandes P, Gertrudes J, Kronenberger T, Honorio K, et al.
J Comput Aided Mol Des . 2023 Oct; 37(12):735-754. PMID: 37804393
QSAR models capable of predicting biological, toxicity, and pharmacokinetic properties were widely used to search lead bioactive molecules in chemical databases. The dataset's preparation to build these models has a...
3.
Flores R, Pantaleao S, Araujo S, Malpartida H, Honorio K
Comput Biol Chem . 2023 Apr; 104:107869. PMID: 37068312
FAM3 is a superfamily of four cytokines that maintain a single globular structure β -β -α of three classes: FAM3A, B, C and D. FAM3C was the first member of...
4.
Pantaleao S, Camillo L, Neves T, Menezes I, Stangherlin L, Batista H, et al.
PLoS One . 2022 Nov; 17(11):e0277953. PMID: 36441804
The human cytomegalovirus (HCMV) UL111A gene encodes several homologs of the cellular interleukin 10 (cIL-10). Alternative splicing in the UL111A region produces two relatively well-characterized transcripts designated cmvIL-10 (isoform A)...
5.
Zarricueta M, Fagundes F, Pereira Q, Pantaleao S, Dos Santos R
Pharmaceutics . 2022 Mar; 14(3). PMID: 35335941
Peptic ulcers are lesions that affect the gastrointestinal tract and that can be triggered by external factors such as alcohol use. This study investigated the gastroprotective role of two anthocyanidins,...
6.
Pantaleao S, Philot E, de Paula H, de Sairre M, Lima A, Pires L, et al.
Biochimie . 2021 Dec; 194:43-50. PMID: 34952193
Diabetes is a metabolic disorder that presents hyperglycemia and vascular complications due to the non-production of insulin or its inappropriate use by the body. One of the strategies to treat...
7.
do Carmo A, Bettanin F, Oliveira Almeida M, Pantaleao S, Rodrigues T, Homem-de-Mello P, et al.
Front Chem . 2020 Apr; 8:235. PMID: 32309275
The study of proteins and mechanisms involved in the apoptosis and new knowledge about cancer's biology are essential for planning new drugs. Tumor cells develop several strategies to gain proliferative...
8.
Pantaleao S, Philot E, de Oliveira Almeida M, Lima A, de Sairre M, Scott A, et al.
Curr Top Med Chem . 2019 Dec; 20(3):209-226. PMID: 31878857
Background: A strategy for the treatment of type II diabetes mellitus is the inhibition of the enzyme known as dipeptidyl peptidase-4 (DPP-4). Aims: This study aims to investigate the main...
9.
Pantaleao S, Philot E, de Resende-Lara P, Lima A, Perahia D, Miteva M, et al.
Molecules . 2018 Feb; 23(2). PMID: 29473857
Dipeptidyl peptidase-4 (DPP-4) is a target to treat type II diabetes mellitus. Therefore, it is important to understand the structural aspects of this enzyme and its interaction with drug candidates....
10.
Pantaleao S, Maltarollo V, Araujo S, Gertrudes J, Honorio K
Mol Biosyst . 2015 Sep; 11(11):3188-93. PMID: 26399297
Dipeptidyl peptidase-4 (DPP-4) is an important biological target related to the treatment of diabetes as DPP-4 inhibitors can lead to an increase in the insulin levels and a prolonged activity...