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Simona Piccirella

Explore the profile of Simona Piccirella including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 358
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Recent Articles
1.
Clark J, Kayed R, Abate G, Uberti D, Kinnon P, Piccirella S
Front Aging Neurosci . 2022 May; 14:835288. PMID: 35572126
Our understanding of Alzheimer's disease (AD) pathogenesis has developed with several hypotheses over the last 40 years, including the Amyloid and Tau hypotheses. More recently, the p53 protein, well-known as...
2.
Abate G, Frisoni G, Bourdon J, Piccirella S, Memo M, Uberti D
Alzheimers Res Ther . 2020 Dec; 12(1):160. PMID: 33272326
Background: Understanding the earliest pathophysiological changes of Alzheimer's disease (AD) may aid in the search for timely diagnostic biomarkers and effective disease-modifying therapies. The p53 protein is mostly known for...
3.
Gianchecchi E, Torelli A, Piccini G, Piccirella S, Montomoli E
Vaccines (Basel) . 2016 May; 4(2). PMID: 27240411
N. meningitidis infections represent a global health problem that can lead to the development of serious permanent sequelae. Although the use of antibiotics and prevention via vaccination have reduced the...
4.
Piccini G, Torelli A, Gianchecchi E, Piccirella S, Montomoli E
Expert Rev Vaccines . 2016 May; 15(11):1393-1407. PMID: 27158988
Neisseria meningitidis infections represent a serious health problem that can lead to invasive meningococcal disease (IMD), a life-threatening condition associated with significant morbidity and mortality. IMD could however be preventable...
5.
Trombetta C, Piccirella S, Perini D, Kistner O, Montomoli E
Vaccines (Basel) . 2015 Sep; 3(1):172-85. PMID: 26344952
In the last 20 years, novel non-seasonal influenza viruses have emerged, most of which have originated from birds. Despite their apparent inability to cause pandemics, with the exception of H1N1...
6.
Gianchecchi E, Torelli A, Piccini G, Piccirella S, Montomoli E
Expert Rev Anti Infect Ther . 2015 Jul; 13(10):1249-63. PMID: 26190347
Neisseria meningitidis is a Gram-negative β-proteobacterium responsible for an endemic worldwide infection. The epidemiology and serogroup distribution can change very quickly. The incidence of meningitis infection varies from very rare...
7.
Trombetta C, Perini D, Vitale L, Cox R, Stanzani V, Piccirella S, et al.
J Immunol Methods . 2015 Apr; 422:95-101. PMID: 25910832
The Single Radial Haemolysis (SRH) assay is a serological method widely used for measuring antibodies against influenza viruses. Despite the broad application and recommendation by licensing authorities, the SRH assay...
8.
Mann A, Noulin N, Catchpole A, Stittelaar K, De Waal L, Veldhuis Kroeze E, et al.
PLoS One . 2014 May; 9(5):e93761. PMID: 24850536
We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI) intratracheal and intranasal challenge in a ferret model....
9.
Svindland S, Pedersen G, Pathirana R, Bredholt G, Nostbakken J, Jul-Larsen A, et al.
Influenza Other Respir Viruses . 2012 Nov; 7(6):1181-93. PMID: 23170900
Background: Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the...
10.
Montomoli E, Khadang B, Piccirella S, Trombetta C, Mennitto E, Manini I, et al.
Expert Rev Vaccines . 2012 Jul; 11(5):587-94. PMID: 22827244
In the 20th century, three influenza pandemics killed approximately 100 million people. The traditional method of influenza vaccine manufacturing is based on using chicken eggs. However, the necessity of the...