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Simon Strobel

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Articles 6
Citations 169
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Recent Articles
1.
Kostadinova R, Strobel S, Chen L, Fiaschetti-Egli K, Gadient J, Pawlowska A, et al.
Sci Rep . 2024 Mar; 14(1):5885. PMID: 38467661
Metabolic dysfunction-associated steatohepatitis (MASH) is a severe liver disease characterized by lipid accumulation, inflammation and fibrosis. The development of MASH therapies has been hindered by the lack of human translational...
2.
Strobel S, Kostadinova R, Fiaschetti-Egli K, Rupp J, Bieri M, Pawlowska A, et al.
Sci Rep . 2021 Nov; 11(1):22765. PMID: 34815444
Non-alcoholic steatohepatitis (NASH) is a progressive and severe liver disease, characterized by lipid accumulation, inflammation, and downstream fibrosis. Despite its increasing prevalence, there is no approved treatment yet available for...
3.
Proctor W, Foster A, Vogt J, Summers C, Middleton B, Pilling M, et al.
Arch Toxicol . 2017 Jun; 91(8):2849-2863. PMID: 28612260
Drug-induced liver injury (DILI) continues to be a major source of clinical attrition, precautionary warnings, and post-market withdrawal of drugs. Accordingly, there is a need for more predictive tools to...
4.
Anastasov N, Hofig I, Radulovic V, Strobel S, Salomon M, Lichtenberg J, et al.
BMC Cancer . 2015 Jun; 15:466. PMID: 26059545
Background: Radiation resistance presents a challenge to the effective treatment of cancer. If therapeutic compounds were capable of resensitizing resistant tumours then a concurrent chemo-radiation treatment could be used to...
5.
Vonwil D, Schuler M, Barbero A, Strobel S, Wendt D, Textor M, et al.
Eur Cell Mater . 2010 Nov; 20:316-28. PMID: 21069635
This study aimed at testing whether an RGD-restricted substrate interface is sufficient for adhesion and growth of human articular chondrocytes (HAC), and whether it enhances their post expansion chondrogenic capacity....
6.
Strobel S, Loparic M, Wendt D, Schenk A, Candrian C, Lindberg R, et al.
Arthritis Res Ther . 2010 Mar; 12(2):R34. PMID: 20193091
Introduction: Oxygen is a critical parameter proposed to modulate the functions of chondrocytes ex-vivo as well as in damaged joints. This article investigates the effect of low (more physiological) oxygen...