Simon Steiger
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Explore the profile of Simon Steiger including associated specialties, affiliations and a list of published articles.
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11
Citations
177
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Recent Articles
1.
Lutz R, Poos A, Sole-Boldo L, John L, Wagner J, Prokoph N, et al.
Sci Immunol
. 2025 Feb;
10(104):eadp6667.
PMID: 39919199
The bone marrow microenvironment plays a crucial role in the development of multiple myeloma. As the disease progresses, malignant myeloma cells can evolve to survive outside the bone marrow. However,...
2.
Lutz R, Grunschlager F, Simon M, Awwad M, Bauer M, Yousefian S, et al.
Nat Commun
. 2024 Nov;
15(1):10396.
PMID: 39613747
The long-term consequences of cancer and its therapy on the patients' immune system years after cancer-free survival remain poorly understood. Here, we present an in-depth characterization of the bone marrow...
3.
Steibl S, Steiger S, Wegmann A, Holmes N, Young H, Carr P, et al.
Nat Ecol Evol
. 2024 Aug;
8(10):1907-1915.
PMID: 39147843
Seabirds play critical roles on islands. By catalysing terrestrial and marine productivity through guano nutrient input, seabirds support natural island functioning. In the Indo-Pacific, atolls comprise one-third of all islands...
4.
Bundschuh C, Weidner N, Klein J, Rausch T, Azevedo N, Telzerow A, et al.
Infect Genet Evol
. 2024 Feb;
119:105577.
PMID: 38403035
In January 2021, the monitoring of circulating variants of SARS-CoV-2 was initiated in Germany under the Corona Surveillance Act, which was discontinued after July 2023. This initiative aimed to enhance...
5.
Schuster L, Syed A, Tirier S, Steiger S, Seufert I, Becker H, et al.
Blood Adv
. 2023 Oct;
7(22):7079-7083.
PMID: 37820244
No abstract available.
6.
John L, Poos A, Brobeil A, Schinke C, Huhn S, Prokoph N, et al.
Nat Commun
. 2023 Aug;
14(1):5011.
PMID: 37591845
In multiple myeloma spatial differences in the subclonal architecture, molecular signatures and composition of the microenvironment remain poorly characterized. To address this shortcoming, we perform multi-region sequencing on paired random...
7.
Poos A, Prokoph N, Przybilla M, Mallm J, Steiger S, Seufert I, et al.
Blood
. 2023 Jun;
142(19):1633-1646.
PMID: 37390336
Intratumor heterogeneity as a clinical challenge becomes most evident after several treatment lines, when multidrug-resistant subclones accumulate. To address this challenge, the characterization of resistance mechanisms at the subclonal level...
8.
Friedrich M, Neri P, Kehl N, Michel J, Steiger S, Kilian M, et al.
Cancer Cell
. 2023 Mar;
41(4):711-725.e6.
PMID: 36898378
Bispecific T cell engagers (TCEs) have shown promise in the treatment of various cancers, but the immunological mechanism and molecular determinants of primary and acquired resistance to TCEs remain poorly...
9.
Huebner A, Gorelov R, Deviatiiarov R, Demharter S, Kull T, Walsh R, et al.
Nat Cell Biol
. 2023 Jan;
25(3):390-403.
PMID: 36717627
The glandular stomach is composed of two regenerative compartments termed corpus and antrum, and our understanding of the transcriptional networks that maintain these tissues is incomplete. Here we show that...
10.
Kehl N, Kilian M, Michel J, Wagner T, Uhrig S, Brobeil A, et al.
J Immunother Cancer
. 2022 Oct;
10(10).
PMID: 36252999
Multiple myeloma (MM) is a hematological malignancy originating from malignant and clonally expanding plasma cells. MM can be molecularly stratified, and its clonal evolution deciphered based on the Ig heavy...