Simon Sieber
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Explore the profile of Simon Sieber including associated specialties, affiliations and a list of published articles.
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23
Citations
182
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Recent Articles
1.
Ren J, Mathew A, Rodriguez-Garcia M, Regli C, Blacque O, Spingler B, et al.
Chembiochem
. 2025 Mar;
:e202400945.
PMID: 40084497
Quorum sensing allows bacteria to coordinate community-wide behaviours such as biofilm formation, virulence, and symbiosis. The diazeniumdiolate valdiazen has been identified in the opportunistic pathogen Burkholderia cenocepacia H111 as a...
2.
Ren J, Mathew A, Rodriguez-Garcia M, Kohler T, Blacque O, Linden A, et al.
Commun Chem
. 2024 Dec;
7(1):301.
PMID: 39702669
Chirality plays a critical role in the biochemistry of life and often only one enantiomeric series is observed (homochirality). Only a few natural products have been obtained as racemates, e.g....
3.
Zdouc M, Blin K, Louwen N, Navarro J, Loureiro C, Bader C, et al.
Nucleic Acids Res
. 2024 Dec;
53(D1):D678-D690.
PMID: 39657789
Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in agriculture, engineering and medicine. Usually, the biosynthesis of these natural products is...
4.
Junier P, Cailleau G, Fatton M, Udriet P, Hashmi I, Bregnard D, et al.
Water Res X
. 2024 Sep;
24:100252.
PMID: 39308956
Over the last two decades, proliferations of benthic cyanobacteria producing derivatives of anatoxin-a have been reported in rivers worldwide. Here, we follow up on such a toxigenic event happening in...
5.
Chokshi K, Kavanagh K, Khan I, Slaveykova V, Sieber S
Environ Int
. 2024 Jun;
189:108813.
PMID: 38878502
Mercury is a highly toxic trace metal that can accumulate in aquatic ecosystems and when resent at high concentrations can pose risks to both aquatic life and humans consuming contaminated...
6.
Mas-Rosello J, Tenor H, Szabo T, Naef R, Sieber S, Gademann K
Chembiochem
. 2024 Mar;
25(8):e202300801.
PMID: 38430555
Inefficient wound healing poses a global health challenge with a lack of efficient treatments. Wound healing issues often correlate with low endogenous nitric oxide (NO) levels. While exogenous delivery with...
7.
Grayfer T, Yamani K, Jung E, Chesnokov G, Ferrara I, Hsiao C, et al.
JACS Au
. 2023 May;
3(4):1151-1161.
PMID: 37124289
Allylic cyclitols were investigated as covalent inhibitors of glycoside hydrolases by chemical, enzymatic, proteomic, and computational methods. This approach was inspired by the C cyclitol natural product streptol glucoside, which...
8.
Danneels B, Blignaut M, Marti G, Sieber S, Vandamme P, Meyer M, et al.
Environ Microbiol
. 2022 Dec;
25(2):454-472.
PMID: 36451580
The symbioses between plants of the Rubiaceae and Primulaceae families with Burkholderia bacteria represent unique and intimate plant-bacterial relationships. Many of these interactions have been identified through PCR-dependent typing methods,...
9.
Schafer R, Wilson K, Biedermann M, Moore B, Sieber S, Wennemers H
Chemistry
. 2022 Nov;
29(6):e202203277.
PMID: 36331430
Isonitrile-containing natural products have garnered attention for their manifold bioactivities but are difficult to detect and isolate due to the chemical lability of the isonitrile functional group. Here, we used...
10.
Muller M, Dorst A, Paulus C, Khan I, Sieber S
Chem Commun (Camb)
. 2022 Oct;
58(90):12560-12563.
PMID: 36264220
Amine-containing natural products are an important class of therapeutic compounds. Herein, we report a chemoselective approach to catch and enrich amine-containing natural products, and release them as underivatized compounds. The...