Simon Schaper
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Explore the profile of Simon Schaper including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
176
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Recent Articles
1.
Izquierdo-Martinez A, Schaper S, Brito A, Liao Q, Tesseur C, Sorg M, et al.
bioRxiv
. 2025 Mar;
PMID: 40027834
Research on chromosome organization and cell cycle progression in spherical bacteria, particularly , remains limited and fragmented. In this study, we established a working model to investigate chromosome dynamics in...
2.
Schaper S, Brito A, Saraiva B, Squyres G, Holmes M, Garner E, et al.
Nat Microbiol
. 2024 Mar;
9(4):1049-1063.
PMID: 38480900
Bacterial cell division requires recruitment of peptidoglycan (PG) synthases to the division site by the tubulin homologue, FtsZ. Septal PG synthases promote septum growth. FtsZ treadmilling is proposed to drive...
3.
Costa S, Saraiva B, Veiga H, Marques L, Schaper S, Sporniak M, et al.
mBio
. 2024 Feb;
15(3):e0323523.
PMID: 38319093
Importance: is a Gram-positive clinical pathogen, which is currently the second cause of death by antibiotic-resistant infections worldwide. For decades, cells were thought to be spherical and lack the ability...
4.
Reed P, Sorg M, Alwardt D, Serra L, Veiga H, Schaper S, et al.
mBio
. 2023 Dec;
15(1):e0277323.
PMID: 38054745
is an important clinical pathogen that causes a high number of antibiotic-resistant infections. The study of biology, and particularly of the function of essential proteins, is of particular importance to...
5.
Veiga H, Jousselin A, Schaper S, Saraiva B, Marques L, Reed P, et al.
EMBO J
. 2023 Apr;
42(11):e112140.
PMID: 37038972
Unregulated cell cycle progression may have lethal consequences and therefore, bacteria have various mechanisms in place for the precise spatiotemporal control of cell cycle events. We have uncovered a new...
6.
Krol E, Schaper S, Becker A
Biol Chem
. 2020 Sep;
401(12):1335-1348.
PMID: 32990642
Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial second messenger which has been associated with a motile to sessile lifestyle switch in many bacteria. Here, we review recent insights into c-di-GMP regulated...
7.
Krol E, Yau H, Lechner M, Schaper S, Bange G, Vollmer W, et al.
mBio
. 2020 Jul;
11(3).
PMID: 32605980
is an alphaproteobacterium belonging to the Bacteria from this order elongate their cell wall at the new cell pole, generated by cell division. Screening for protein interaction partners of the...
8.
Schaper S, Wendt H, Bamberger J, Sieber V, Schmid J, Becker A
J Bacteriol
. 2019 Mar;
201(10).
PMID: 30833352
produces multiple extracellular glycans, including among others, lipopolysaccharides (LPS), and the exopolysaccharides (EPS) succinoglycan (SG) and galactoglucan (GG). These polysaccharides serve cell protective roles. Furthermore, SG and GG promote the...
9.
Schaper S, Yau H, Krol E, Skotnicka D, Heimerl T, Gray J, et al.
PLoS Genet
. 2018 Aug;
14(8):e1007594.
PMID: 30102748
Members of the Rhizobiales (class of α-proteobacteria) display zonal peptidoglycan cell wall growth at one cell pole, contrasting with the dispersed mode of cell wall growth along the sidewalls of...
10.
Schaper S, Steinchen W, Krol E, Altegoer F, Skotnicka D, Sogaard-Andersen L, et al.
Proc Natl Acad Sci U S A
. 2017 Jun;
114(24):E4822-E4831.
PMID: 28559336
Cyclic dimeric GMP (c-di-GMP) has emerged as a key regulatory player in the transition between planktonic and sedentary biofilm-associated bacterial lifestyles. It controls a multitude of processes including production of...