Simon P Duffy
Overview
Explore the profile of Simon P Duffy including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
560
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0
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Recent Articles
1.
Jang D, Matthews K, Deng P, Berryman S, Nian C, Duffy S, et al.
Lab Chip
. 2024 Aug;
24(18):4232-4241.
PMID: 39212929
Pancreatic β cells secrete insulin in response to elevated levels of glucose. Stem cell derived β (SCβ) cells aim to replicate this glucose-stimulated insulin secretion (GSIS) function, but current preparations...
2.
Lamoureux E, Cheng Y, Islamzada E, Matthews K, Duffy S, Ma H
Heliyon
. 2024 Aug;
10(15):e35276.
PMID: 39170127
Microscopic inspection of thin-film blood smears is widely used to identify red blood cell (RBC) pathologies, including malaria parasitism and hemoglobinopathies, such as sickle cell disease and thalassemia. Emerging research...
3.
Deng P, Xu A, Grin P, Matthews K, Duffy S, Ma H
Commun Biol
. 2024 Mar;
7(1):386.
PMID: 38553656
The release of cellular DNA as neutrophil extracellular traps (NETs) plays a pivotal role in the immune response to pathogens by physically entrapping and killing microbes. NET release occurs at...
4.
Lamoureux E, Islamzada E, Wiens M, Matthews K, Duffy S, Ma H
Data Brief
. 2023 Feb;
47:108928.
PMID: 36798597
Red blood cell (RBC) deformability is a vital biophysical property that dictates the ability of these cells to repeatedly squeeze through small capillaries in the microvasculature. This capability is known...
5.
Lee J, Park E, Choi J, Matthews K, Lam A, Deng X, et al.
Commun Biol
. 2022 Jul;
5(1):768.
PMID: 35908100
Single cell RNA sequencing has the potential to elucidate transcriptional programs underlying key cellular phenotypes and behaviors. However, many cell phenotypes are incompatible with indiscriminate single cell sequencing because they...
6.
Islamzada E, Matthews K, Lamoureux E, Duffy S, Scott M, Ma H
EJHaem
. 2022 Jul;
3(1):63-71.
PMID: 35846223
Red blood cells (RBCs) stored in blood bags develop a storage lesion that include structural, metabolic, and morphologic transformations resulting in a progressive loss of RBC deformability. The speed of...
7.
Lee R, Witherspoon L, Robinson M, Lee J, Duffy S, Flannigan R, et al.
Fertil Steril
. 2022 May;
118(1):90-99.
PMID: 35562203
Objective: To develop a machine learning algorithm to detect rare human sperm in semen and microsurgical testicular sperm extraction (microTESE) samples using bright-field (BF) microscopy for nonobstructive azoospermia patients. Design:...
8.
Matthews K, Lamoureux E, Myrand-Lapierre M, Duffy S, Ma H
Lab Chip
. 2022 Mar;
22(7):1254-1274.
PMID: 35266475
Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly deform through capillaries as small as 2 μm in order to deliver oxygen to all parts...
9.
Islamzada E, Matthews K, Lamoureux E, Duffy S, Scott M, Ma H
Transfusion
. 2021 Dec;
62(2):448-456.
PMID: 34877683
Background: The biophysical properties of red blood cells (RBCs) provide potential biomarkers for the quality of donated blood. Blood unit segments provide a simple and nondestructive way to sample RBCs...
10.
Lamoureux E, Islamzada E, Wiens M, Matthews K, Duffy S, Ma H
Lab Chip
. 2021 Dec;
22(1):26-39.
PMID: 34874395
Red blood cells (RBCs) must be highly deformable to transit through the microvasculature to deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural aging, or storage...