Simon OKeefe
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Explore the profile of Simon OKeefe including associated specialties, affiliations and a list of published articles.
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6
Citations
64
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Recent Articles
1.
Rusilowicz M, Dickinson M, Charlton A, OKeefe S, Wilson J
PLoS One
. 2018 Oct;
13(10):e0205968.
PMID: 30372459
Motivation: Modern analytical techniques such as LC-MS, GC-MS and NMR are increasingly being used to study the underlying dynamics of biological systems by tracking changes in metabolite levels over time....
2.
Rusilowicz M, Dickinson M, Charlton A, OKeefe S, Wilson J
Metabolomics
. 2016 Apr;
12:56.
PMID: 27069441
The need for reproducible and comparable results is of increasing importance in non-targeted metabolomic studies, especially when differences between experimental groups are small. Liquid chromatography-mass spectrometry spectra are often acquired...
3.
Kirkwood J, Hargreaves D, OKeefe S, Wilson J
Acta Crystallogr F Struct Biol Commun
. 2015 Oct;
71(Pt 10):1228-34.
PMID: 26457511
The Protein Data Bank (PDB) is the largest available repository of solved protein structures and contains a wealth of information on successful crystallization. Many centres have used their own experimental...
4.
Hodge V, OKeefe S, Austin J
Neural Netw
. 2015 Sep;
78:24-35.
PMID: 26403824
In this paper, we introduce a theoretical basis for a Hadoop-based neural network for parallel and distributed feature selection in Big Data sets. It is underpinned by an associative memory...
5.
Kirkwood J, Hargreaves D, OKeefe S, Wilson J
Bioinformatics
. 2015 Jan;
31(9):1444-51.
PMID: 25573921
Motivation: The identification of suitable conditions for crystallization is a rate-limiting step in protein structure determination. The pH of an experiment is an important parameter and has the potential to...
6.
Kirkwood J, Wilson J, OKeefe S, Hargreaves D
Acta Crystallogr D Biol Crystallogr
. 2014 Sep;
70(Pt 9):2367-75.
PMID: 25195750
The crystallization of proteins is dependent on the careful control of numerous parameters, one of these being pH. The pH of crystallization is generally reported as that of the buffer;...