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Simon M Cutting

Explore the profile of Simon M Cutting including associated specialties, affiliations and a list of published articles. Areas
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Articles 74
Citations 2286
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Recent Articles
1.
Horwell E, Vittoria M, Hong H, Bearn P, Cutting S
Dig Dis Sci . 2024 Aug; 69(10):3729-3741. PMID: 39110366
Background: The Bacillus-derived cyclic lipopeptides (surfactin, iturin, and fengycin) form potent Heterogeneous Lipopeptide Micelle (HeLM) complexes. HeLM is a small molecule that has been shown to have immunomodulatory effects. However,...
2.
Ho Y, Hynes D, Martina Y, Love B, Horwell E, Xu R, et al.
J Med Microbiol . 2024 Jul; 73(7). PMID: 38963177
Administered nasally, spores of the Gram-positive bacterium have been shown to be able to induce innate immunity sufficient to confer protection to influenza and respiratory syncytial virus. Although members of...
3.
Nguyen T, Do H, Nguyen T, Pham T, Mach B, Nguyen T, et al.
J Med Microbiol . 2024 Jan; 73(1). PMID: 38235783
infection is a major global health concern, linked to the development of various gastrointestinal diseases, including gastric cancer. To study the pathogenesis of and develop effective intervention strategies, appropriate animal...
4.
White A, Tran A, Sibley L, Sarfas C, Morrison A, Lawrence S, et al.
Front Immunol . 2023 Oct; 14:1246826. PMID: 37881438
Tuberculosis remains a major health threat globally and a more effective vaccine than the current Bacillus Calmette Guerin (BCG) is required, either to replace or boost it. The Spore-FP1 mucosal...
5.
Larsen I, Chenaux M, Collins F, Mandic A, Hansen L, Lauridsen C, et al.
Sci Rep . 2023 Sep; 13(1):14941. PMID: 37696924
Up to 25% of the US population harbor Clostridioides difficile in the gut. Following antibiotic disruption of the gut microbiota, C. difficile can act as an opportunistic pathogen and induce...
6.
Katsande P, Nguyen V, Nguyen T, Nguyen T, Mills G, Bailey D, et al.
Helicobacter . 2023 Jun; 28(4):e12997. PMID: 37314018
Background: Helicobacter pylori infection remains a major public health threat leading to gastrointestinal illness and increased risk of gastric cancer. Mostly affecting populations in developing countries no vaccines are yet...
7.
Katsande P, Fernandez-Bastit L, Ferreira W, Vergara-Alert J, Hess M, Lloyd-Jones K, et al.
Vaccines (Basel) . 2022 Nov; 10(11). PMID: 36366408
: Current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are administered systemically and typically result in poor immunogenicity at the mucosa. As a result, vaccination is unable to reduce...
8.
James J, Meyer S, Hong H, Dang C, Linh H, Ferreira W, et al.
Vaccines (Basel) . 2022 Sep; 10(9). PMID: 36146637
Influenza is a respiratory infection that continues to present a major threat to human health, with ~500,000 deaths/year. Continued circulation of epidemic subtypes in humans and animals potentially increases the...
9.
Ferreira W, Hong H, Adams J, Hess M, Kotowicz N, Tan S, et al.
Biomedicines . 2022 May; 10(5). PMID: 35625667
is an environmentally acquired, anaerobic, spore-forming bacterium which ordinarily causes disease following antibiotic-mediated dysbiosis of the intestinal microbiota. Although much is understood regarding the life cycle of , the fate...
10.
Ferreira W, Hong H, Hess M, Adams J, Wood H, Bakun K, et al.
Pharmaceutics . 2021 Aug; 13(8). PMID: 34452257
Members of the genus, particularly the " group", are known to produce amphipathic lipopeptides with biosurfactant activity. This includes the surfactins, fengycins and iturins that have been associated with antibacterial,...