Simon L Wuest
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Explore the profile of Simon L Wuest including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
223
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Recent Articles
1.
Salvadori V, Fah D, Fluhler S, Wandeler J, Jacome M, Koller A, et al.
HardwareX
. 2024 Nov;
20:e00593.
PMID: 39512419
Light microscopes became essential tools in everyday lab work a long time ago. However, most commercial microscopes are costly, and they are often bulky and heavy. Therefore, microscopes are rarely...
2.
Graf J, Schulz H, Wehland M, Corydon T, Sahana J, Abdelfattah F, et al.
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255998
Cancer is defined as a group of diseases characterized by abnormal cell growth, expansion, and progression with metastasis. Various signaling pathways are involved in its development. Malignant tumors exhibit a...
3.
Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine
Cortes-Sanchez J, Melnik D, Sandt V, Kahlert S, Marchal S, Johnson I, et al.
Cells
. 2023 Nov;
12(22).
PMID: 37998400
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ...
4.
Hammer A, Cerretti G, Ricciardi D, Schiffmann D, Maranda S, Kummer R, et al.
Biomedicines
. 2022 Jan;
10(1).
PMID: 35052817
Calcium (Ca) elevation is an essential secondary messenger in many cellular processes, including disease progression and adaptation to external stimuli, e.g., gravitational load. Therefore, mapping and quantifying Ca signaling with...
5.
Wuest S, Calio M, Wernas T, Tanner S, Giger-Lange C, Wyss F, et al.
Int J Mol Sci
. 2018 Apr;
19(5).
PMID: 29693628
Due to the limited self-repair capacity of articular cartilage, the surgical restoration of defective cartilage remains a major clinical challenge. The cell-based approach, which is known as autologous chondrocyte transplantation...
6.
Wuest S, Gantenbein B, Ille F, Egli M
NPJ Microgravity
. 2018 Apr;
4:7.
PMID: 29619409
Advances in electrophysiological experiments have led to the discovery of mechanosensitive ion channels (MSCs) and the identification of the physiological function of specific MSCs. They are believed to play important...
7.
Wuest S, Stern P, Casartelli E, Egli M
PLoS One
. 2017 Jan;
12(1):e0170826.
PMID: 28135286
Random Positioning Machines (RPMs) are widely used as tools to simulate microgravity on ground. They consist of two gimbal mounted frames, which constantly rotate biological samples around two perpendicular axes...
8.
Wuest S, Richard S, Kopp S, Grimm D, Egli M
Biomed Res Int
. 2015 Feb;
2015:971474.
PMID: 25649075
Random Positioning Machines (RPMs) have been used since many years as a ground-based model to simulate microgravity. In this review we discuss several aspects of the RPM. Recent technological development...
9.
Benavides Damm T, Walther I, Wuest S, Sekler J, Egli M
Biotechnol Bioeng
. 2013 Dec;
111(6):1180-90.
PMID: 24375199
Important in biotechnology is the establishment of cell culture methods that reflect the in vivo situation accurately. One approach for reaching this goal is through 3D cell cultivation that mimics...