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Siming Yuan

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Articles 41
Citations 239
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Recent Articles
1.
Wang C, Wu H, Xie Y, Wang J, Huang L, Ni X, et al.
Phytother Res . 2025 Feb; 39(3):1615-1631. PMID: 39916312
Background: Diabetic nephropathy (DN) stands as one of the most severe complications of diabetes. Podocytes injury, particularly its attachment to the lateral glomerular basement membrane, serves as a crucial indicator...
2.
Deng S, Huang L, Shao Y, Xie Y, Yuan S, Tang L
Cell Signal . 2025 Jan; 127:111611. PMID: 39842531
Diabetic kidney disease (DKD) is a chronic complication of diabetes characterized by kidney damage due to persistent hyperglycemia. A growing number of evidence indicated that circular RNAs (circRNAs) play a...
3.
Wang S, Gao D, Li M, Wang Q, Du X, Yuan S
Biomedicines . 2025 Jan; 12(12. PMID: 39767750
Background: Burns and chronic ulcers may cause severe skin loss, leading to critical health issues like shock, infection, sepsis, and multiple organ failure. Effective healing of full-thickness wounds may be...
4.
Wang S, Yuan S, Hu H, Zhang J, Cao K, Wang Y, et al.
Inorg Chem . 2024 Jun; 63(25):11779-11787. PMID: 38850241
Cisplatin is a widely used anticancer drug. In addition to inducing DNA damage, increased levels of reactive oxygen species (ROS) play a significant role in cisplatin-induced cell death. Thioredoxin-1 (Trx1),...
5.
Wang S, Yuan S
Front Pediatr . 2024 Mar; 12:1336358. PMID: 38500592
Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies (CLOVES) constitute a rare overgrowth disorder resulting from a mosaic function-acquiring mutation in the gene. Targeted drugs for the PI3K-AKT...
6.
Yang L, Yuan S, Wang R, Guo X, Xie Y, Wei W, et al.
Int Immunopharmacol . 2023 Nov; 126:111237. PMID: 37977063
Background And Purpose: Diabetic nephropathy (DN) is a prevalent complication of diabetes mellitus characterized by hyperglycemia, hyperlipidemia, albuminuria and edema. Increasing evidence indicated that berberine (BBR) could alleviate the occurrence...
7.
Wang Y, Cao K, Zong M, Yuan S, Zhang N, Liu Y
Nucleic Acids Res . 2023 Oct; 52(1):288-299. PMID: 37897365
Liquid-liquid phase separation (LLPS) of G-quadruplex (GQ) is involved in many crucial cellular processes, while the quadruplex-folding and their functions are typically modulated by specific DNA-binding proteins. However, the regulatory...
8.
Shao Y, Deng S, Tang W, Huang L, Xie Y, Yuan S, et al.
Int Immunopharmacol . 2023 Jul; 122:110632. PMID: 37451013
Diabetic nephropathy (DN), a chronic progressive kidney disease, is the most prevalent microvascular complication associated with diabetes which causes the end-stage renal disease. Glomerular endothelial cells (GECs) are one of...
9.
Luan M, Hou Z, Zhang B, Ma L, Yuan S, Liu Y, et al.
Anal Chem . 2023 Jun; 95(23):8798-8806. PMID: 37309130
The mechanisms whereby protein ions are released from nanodroplets at the liquid-gas interface have continued to be controversial since electrospray ionization (ESI) mass spectrometry was widely applied in biomolecular structure...
10.
Wang Y, Yuan S, Cao K, Liu Y
Metallomics . 2023 Mar; 15(4). PMID: 36906278
Protein reactions play important roles in the mechanism of action of cisplatin. In this work, we found that cisplatin is highly reactive to the RING finger domain of RNF11, a...