Silvia R Vitale
Overview
Explore the profile of Silvia R Vitale including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
160
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0
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Recent Articles
1.
Vitale S, Ruigrok-Ritstier K, Timmermans A, Foekens R, Trapman-Jansen A, Beaufort C, et al.
BMC Cancer
. 2022 Feb;
22(1):165.
PMID: 35151276
Background: In breast cancer (BC), recurrent fusion genes of estrogen receptor alpha (ESR1) and AKAP12, ARMT1 and CCDC170 have been reported. In these gene fusions the ligand binding domain of...
2.
Vitale S, Helmijr J, Gerritsen M, Coban H, van Dessel L, Beije N, et al.
BMC Cancer
. 2021 Mar;
21(1):315.
PMID: 33761899
Background: Extracellular vesicles (EVs) are actively secreted by cells into body fluids and contain nucleic acids of the cells they originate from. The goal of this study was to detect...
3.
Vitale S, Groenendijk F, van Marion R, Beaufort C, Helmijr J, Dubbink H, et al.
Biomolecules
. 2020 Mar;
10(3).
PMID: 32156073
The aim of this study was to determine an optimal workflow to detect mutations in baseline and longitudinal serum cell free DNA (cfDNA) from high-grade serous ovarian carcinomas (HGSOC) patients...
4.
van Dessel L, Vitale S, Helmijr J, Wilting S, van der Vlugt-Daane M, Oomen-de Hoop E, et al.
Mol Oncol
. 2018 Dec;
13(2):392-402.
PMID: 30516338
The emerging interest in circulating tumor DNA (ctDNA) analyses for clinical trials has necessitated the development of a high-throughput method for fast, reproducible, and efficient isolation of ctDNA. Currently, the...
5.
An Optimized Workflow to Evaluate Estrogen Receptor Gene Mutations in Small Amounts of Cell-Free DNA
Vitale S, Sieuwerts A, Beije N, Kraan J, Angus L, Mostert B, et al.
J Mol Diagn
. 2018 Oct;
21(1):123-137.
PMID: 30296589
The detection of mutated genes in cell-free DNA (cfDNA) in plasma has emerged as an important minimally invasive way to obtain detailed information regarding tumor biology. Reliable determination of circulating...
6.
Beije N, Sieuwerts A, Kraan J, Van N, Onstenk W, Vitale S, et al.
Mol Oncol
. 2017 Oct;
12(1):48-57.
PMID: 29063679
Mutations and splice variants in the estrogen receptor (ER) gene, ESR1, may yield endocrine resistance in metastatic breast cancer (MBC) patients. These putative endocrine resistance markers are likely to emerge...
7.
van Dessel L, Beije N, Helmijr J, Vitale S, Kraan J, Look M, et al.
Mol Oncol
. 2017 Feb;
11(3):295-304.
PMID: 28164427
Circulating tumor DNA (ctDNA) has emerged as a potential new biomarker with diagnostic, predictive, and prognostic applications for various solid tumor types. Before beginning large prospective clinical trials to prove...